Dimethyl cyclobutane-1,2-dicarboxylate

Base Information

Chemical Name:Dimethyl cyclobutane-1,2-dicarboxylate
CAS No.:3396-20-1
Molecular Formula:C₈H₁₂O₄
Molecular Weight:172.181
Hs Code.:2917209090
NSC Number:527269
UNII:NS4GT4WQQ8
DSSTox Substance ID:DTXSID90948947
Nikkaji Number:J124.805G
Mol file:3396-20-1.mol

Synonyms:Dimethyl cyclobutane-1,2-dicarboxylate;3396-20-1;1,2-Cyclobutanedicarboxylic acid, dimethyl ester;NS4GT4WQQ8;2607-03-6;1,2-dimethyl cyclobutane-1,2-dicarboxylate;NSC-527269;METHYL CYCLOBUTANE-1,2-DICARBOXYLATE;dimethyl(1R,2R)-cyclobutane-1,2-dicarboxylate;Cyclobutane-1,2-dicarboxylic acid dimethyl ester;1,2-Cyclobutanedicarboxylic acid, dimethyl ester, cis-;trans-1,2-Dimethyl-cyclobutane-1,2-dicarboxylate;UNII-NS4GT4WQQ8;USAF ST-7;Cyclobutane-1,2-dicarboxylic acid, dimethyl ester;SCHEMBL8226507;NIOSH/GU1753000;AMY7484;DTXSID90948947;CAA60703;CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS;NSC527269;AKOS006275951;NSC 527269;PB42418;SB22499;SB22500;Dimethyl 1,2-cyclobutanedicarboxylate #;AS-69928;cis-Dimethyl 1,2-Cyclobutanedicarboxylate;LS-55881;CS-0045484;FT-0694962;FT-0697003;GU17530000;1,2-Cyclobutanedicarboxylic acid dimethyl ester;A912365;1,2-Cyclobutanedicarboxylic acid, 1,2-dimethyl ester;Cyclobutane-1,2-dicarBOXYLIC acidDimethyl ester,Trans;Trans-1,2-cyclobutanedicarboxylic acid, dimethyl ester

Suppliers and Price of Dimethyl cyclobutane-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Dimethylcyclobutane-1,2-dicarboxylate 97%
1g
$ 661.00

Chemenu
dimethylcyclobutane-1,2-dicarboxylate 95+%
1g
$ 625.00

American Custom Chemicals Corporation
(1R,2R)-DIMETHYL CYCLOBUTANE-1,2-DICARBOXYLATE 95.00%
5MG
$ 500.19

ACHEMBLOCK
1,2-dimethylcyclobutane-1,2-dicarboxylate 97%
250MG
$ 325.00

Total 11 raw suppliers

Chemical Property of Dimethyl cyclobutane-1,2-dicarboxylate

Chemical Property:

Boiling Point:224.8°Cat760mmHg
Flash Point:105.9°C
PSA：52.60000
Density:1.177g/cm³
LogP:0.35860
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:172.07355886
Heavy Atom Count:12
Complexity:177

Purity/Quality:

97% ^*data from raw suppliers

Dimethylcyclobutane-1,2-dicarboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CCC1C(=O)OC

Technology Process of Dimethyl cyclobutane-1,2-dicarboxylate

There total 3 articles about Dimethyl cyclobutane-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1128-10-5
1,2-dicarbomethoxycyclobutene

: 3396-20-1
dimethyl cyclobutane-1,2-dicarboxylate

Guidance literature:: With triethylsilane; In tetrahydrofuran; for 6h; Reflux;

Reference yield:

: 868-72-4,53490-47-4,124819-17-6
dimethyl 2,5-dibromohexanedioate

: 3396-20-1
dimethyl cyclobutane-1,2-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 36 h / 120 °C / Large scale

2: triethylsilane / tetrahydrofuran / 6 h / Reflux

With triethylsilane; caesium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;