Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide

Base Information

Chemical Name:Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide
CAS No.:136603-11-7
Molecular Formula:C₂₃H₁₈N₄O₃
Molecular Weight:398.421
Hs Code.:
DSSTox Substance ID:DTXSID60159846
Wikidata:Q83028221

Synonyms:BRN 4887662;Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide;(4-((2-Phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)acetic acid hydrazide;136603-11-7;DTXSID60159846;C23-H18-N4-O3

Suppliers and Price of Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide

Chemical Property:

Vapor Pressure:1.89E-21mmHg at 25°C
Boiling Point:734.8°Cat760mmHg
Flash Point:398.2°C
Density:1.312g/cm³
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:398.13789045
Heavy Atom Count:30
Complexity:587

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C=C3C=CC=NC3=N2)C(=O)C4=CC=C(C=C4)OCC(=O)NN

Technology Process of Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide

There total 4 articles about Acetic acid, (4-((2-phenyl-1,8-naphthyridin-3-yl)carbonyl)phenoxy)-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 136603-10-6
Ethyl p-(3-benzoyl-2-phenyl-1,8-naphthyridinyl)methoxyacetate

: 136603-11-7
p-(3-Benzoyl-2-phenyl-1,8-naphthyridinyl)methoxyacetylhydrazine

Guidance literature:: With hydrazine hydrate; In methanol; for 8h; Heating;

Reference yield:

: 7521-41-7
2-Aminonicotinaldehyde

: 136603-11-7
p-(3-Benzoyl-2-phenyl-1,8-naphthyridinyl)methoxyacetylhydrazine

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄, glac. AcOH

2: 65 percent / K₂CO₃ / acetone / 18 h / Heating

3: 60 percent / hydrazine hydrate / methanol / 8 h / Heating

With sulfuric acid; potassium carbonate; hydrazine hydrate; acetic acid; In methanol; acetone;

Reference yield:

: 52046-71-6
1-(4-hydroxy-phenyl)-3-phenyl-propane-1,3-dione

: 136603-11-7
p-(3-Benzoyl-2-phenyl-1,8-naphthyridinyl)methoxyacetylhydrazine

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄, glac. AcOH

2: 65 percent / K₂CO₃ / acetone / 18 h / Heating

3: 60 percent / hydrazine hydrate / methanol / 8 h / Heating

With sulfuric acid; potassium carbonate; hydrazine hydrate; acetic acid; In methanol; acetone;