6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Base Information

Chemical Name:6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione
CAS No.:6258-48-6
Molecular Formula:C14H13NO6
Molecular Weight:291.26
Hs Code.:
DSSTox Substance ID:DTXSID50540128

Synonyms:6258-48-6;DTXSID50540128;6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Suppliers and Price of 6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:291.07428713
Heavy Atom Count:21
Complexity:480

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(OC(=O)C2(CC2C3=CC=C(C=C3)[N+](=O)[O-])C(=O)O1)C

Technology Process of 6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

There total 4 articles about 6,6-Dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 100-13-0
4-nitrostyrene

: 34107-52-3
2,2-dimethyl-5-(phenyl-λ³-iodaneylidene)-1,3-dioxane-4,6-dione

: 6258-48-6
6,6-dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Guidance literature:: In acetonitrile; at 25 ℃; for 28h; chemoselective reaction; Inert atmosphere; Irradiation;
DOI:10.1002/anie.201908994

Reference yield: 67.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 15795-62-7
2,2-dimethyl-5-(4-nitrobenzylidene)-1,3-dioxane-4,6-dione

: 6258-48-6
6,6-dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Guidance literature:: In methanol; diethyl ether; at -70 ℃; for 1h;
DOI:10.1016/S0040-4020(01)83489-X

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 6258-48-6
6,6-dimethyl-1-(4-nitrophenyl)-5,7-dioxaspiro[2.5]octane-4,8-dione

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2: acetonitrile / 28 h / 25 °C / Inert atmosphere; Irradiation

In dichloromethane; acetonitrile;
DOI:10.1002/anie.201908994