2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester

Base Information

Chemical Name:2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester
CAS No.:62664-91-9
Molecular Formula:C13H17NO2
Molecular Weight:219.28000
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00400687
Mol file:62664-91-9.mol

Synonyms:62664-91-9;METHYL 1-(2-PHENYLETHYL)-2-AZETIDINECARBOXYLATE;2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester;SCHEMBL2772130;DTXSID00400687

Suppliers and Price of 2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester

Chemical Property:

PSA：29.54000
LogP:1.41430
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:236

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CCN1CCC2=CC=CC=C2

Technology Process of 2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester

There total 1 articles about 2-Azetidinecarboxylic acid, 1-(2-phenylethyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 29547-04-4,70288-65-2
methyl 2,4-dibromobutanoate

: 64-04-0
phenethylamine

: 62664-91-9
N-(2-Phenethyl)-2-(carbomethoxy)azetidine

Guidance literature:: In acetonitrile; 1.) 25 deg C, 1h, 2.) 55 deg C, 24h;
DOI:10.1021/jo00328a001

Reference yield: 94.0%

: 62664-91-9
N-(2-Phenethyl)-2-(carbomethoxy)azetidine

: 62664-95-3
N-Phenethylazetidine-2-carboxylic acid

Guidance literature:: With barium dihydroxide; In water; for 1h; Heating;
DOI:10.1021/jo00328a001

Reference yield:

: 62664-91-9
N-(2-Phenethyl)-2-(carbomethoxy)azetidine

: 62664-99-7
N-(2-Phenethyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Ba(OH)2*8H₂O / H₂O / 1 h / Heating

2: 1.) LDA, 3.) TsOH / 1.) THF, 0 deg C, 1h, 2.) photooxygenation/ether, -78 deg C, 3.) THF, -78 deg C

With barium dihydroxide; toluene-4-sulfonic acid; lithium diisopropyl amide; In water;
DOI:10.1021/jo00328a001