1-Phenylpenta-1,4-diyn-3-ol

Base Information

Chemical Name:1-Phenylpenta-1,4-diyn-3-ol
CAS No.:62679-57-6
Molecular Formula:C11H8O
Molecular Weight:156.184
Hs Code.:
DSSTox Substance ID:DTXSID10440271
Nikkaji Number:J1.878.951E

Synonyms:1-phenylpenta-1,4-diyn-3-ol;62679-57-6;1,4-Pentadiyn-3-ol, 1-phenyl-;DTXSID10440271;1-Ethynyl-3-phenyl-2-propyne-1-ol

Suppliers and Price of 1-Phenylpenta-1,4-diyn-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-Phenylpenta-1,4-diyn-3-ol

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:156.057514874
Heavy Atom Count:12
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC(C#CC1=CC=CC=C1)O

Technology Process of 1-Phenylpenta-1,4-diyn-3-ol

There total 12 articles about 1-Phenylpenta-1,4-diyn-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 2579-22-8
Phenylpropargyl aldehyde

: 4301-14-8
acetylenemagnesium bromide

: 62679-57-6
1-phenylpenta-1,4-diyn-3-ol

Guidance literature:: acetylenemagnesium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -40 - 0 ℃; for 0.5h;

Phenylpropargyl aldehyde; In tetrahydrofuran; at -78 - 20 ℃;
DOI:10.1021/acs.orglett.0c02892

Reference yield: 80.0%

: 2975-46-4
3-(trimethylsilyl)prop-2-yn-1-al

: 536-74-3
phenylacetylene

: 62679-57-6
1-phenylpenta-1,4-diyn-3-ol

Guidance literature:: phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

3-(trimethylsilyl)prop-2-yn-1-al; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 0 ℃; for 2h;
DOI:10.1002/adsc.201600684

Reference yield: 67.0%

: 2579-22-8
Phenylpropargyl aldehyde

: 74-86-2,25067-58-7
acetylene

: 62679-57-6
1-phenylpenta-1,4-diyn-3-ol

Guidance literature:: acetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

Phenylpropargyl aldehyde; In tetrahydrofuran; hexane; at -78 - -30 ℃; for 2h; Inert atmosphere;
DOI:10.1002/anie.201310146