2-(3-Chloro-2-fluorophenoxy)acetic acid

Base Information

Chemical Name:2-(3-Chloro-2-fluorophenoxy)acetic acid
CAS No.:447-49-4
Molecular Formula:C₈H₆ClFO₃
Molecular Weight:204.585
Hs Code.:
NSC Number:190670
DSSTox Substance ID:DTXSID20307301
Wikidata:Q82054676

Synonyms:2-(3-chloro-2-fluorophenoxy)acetic acid;447-49-4;NSC190670;DTXSID20307301;(3-Chloro-2-fluorophenoxy)acetic acid;NSC-190670;2-(3-chloro-2-fluorophenoxy)aceticacid;EN300-299809;Z1416192912

Suppliers and Price of 2-(3-Chloro-2-fluorophenoxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-(3-Chloro-2-fluorophenoxy)acetic acid

Chemical Property:

Vapor Pressure:7.79E-05mmHg at 25°C
Boiling Point:328.2°Cat760mmHg
Flash Point:152.3°C
Density:1.453g/cm³
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:203.9989499
Heavy Atom Count:13
Complexity:188

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Cl)F)OCC(=O)O

Technology Process of 2-(3-Chloro-2-fluorophenoxy)acetic acid

There total 4 articles about 2-(3-Chloro-2-fluorophenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3209-22-1
1,2-Dichloro-3-nitrobenzene

: 447-49-4
(3-chloro-2-fluoro-phenoxy)-acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylformamide; potassium fluoride / 150 °C

2: iron

3: sulfuric acid; sodium nitrite / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und wss. Schwefelsaeure auf 170grad

4: aq. NaOH solution

With potassium fluoride; sodium hydroxide; sulfuric acid; iron; N,N-dimethyl-formamide; sodium nitrite;
DOI:10.1021/ja01510a021

Reference yield:

: 2106-49-2
1-chloro-2-fluoro-3-nitrobenzene

: 447-49-4
(3-chloro-2-fluoro-phenoxy)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: iron

2: sulfuric acid; sodium nitrite / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und wss. Schwefelsaeure auf 170grad

3: aq. NaOH solution

With sodium hydroxide; sulfuric acid; iron; sodium nitrite;
DOI:10.1021/ja01510a021

Reference yield:

: 2106-04-9
3-chloro-2-fluoroaniline

: 447-49-4
(3-chloro-2-fluoro-phenoxy)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; sodium nitrite / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und wss. Schwefelsaeure auf 170grad

2: aq. NaOH solution

With sodium hydroxide; sulfuric acid; sodium nitrite;
DOI:10.1021/ja01510a021