Isopiperine

Base Information

• Chemical Name: Isopiperine
• CAS No.: 30511-76-3
• Molecular Formula: C₁₇H₁₉NO₃
• Molecular Weight: 285.343
• NSC Number: 242267
• UNII: Z3C7H03C5M
• Nikkaji Number: J729.959A
• Wikidata: Q27294941
• Mol file: 30511-76-3.mol

Synonyms:Isopiperine;UNII-Z3C7H03C5M;Z3C7H03C5M;30511-76-3;Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-, (Z,E)-;SCHEMBL14171509;N17H19NO3;1-[5-(3,4-pentadienyl]piperidine;N17-H19-N-O3;NSC242267;NSC-242267;EN300-27122038;Q27294941;Piperidine,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-;Piperidine,4-methylenedioxyphenyl)-1-oxo-2,4-pentadienyl]-;(2Z,4E)-5-(1,3-dioxaindan-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one;2,4-PENTADIEN-1-ONE, 5-(1,3-BENZODIOXOL-5-YL)-1-(1-PIPERIDINYL)-, (2Z,4E)-;PIPERIDINE, 1-((2Z,4E)-5-(1,3-BENZODIOXOL-5-YL)-1-OXO-2,4-PENTADIENYL)-

Chemical Property of Isopiperine

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 285.13649347
• Heavy Atom Count: 21
• Complexity: 412

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3
• Isomeric SMILES: C1CCN(CC1)C(=O)/C=C\C=C\C2=CC3=C(C=C2)OCO3

Technology Process of Isopiperine

There total 3 articles about Isopiperine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Piperine (94-62-2,7780-20-3) → Isochavicine (30511-77-4,7780-20-3) + Isopeperine (30511-76-3,7780-20-3) + 1-(2Z,4Z)-piperinoyl-piperidine (495-91-0,7780-20-3)

Guidance literature:

In methanol; at 25 ℃; for 72h; Further Variations:; light intensities; time; Product distribution; UV-irradiation;

DOI:10.1021/jf070831p

Reference yield:

1,2,3-trithiaphenalene-2-oxide + Piperine (94-62-2,7780-20-3) → Isochavicine (30511-77-4,7780-20-3) + Isopeperine (30511-76-3,7780-20-3) + 1,8-naphthalenedisulfide (209-22-3) + (5-(benzo[d][1,3]dioxol-5-yl)thiophen-2-yl)(piperidin-1-yl)methanone

Guidance literature:

In chlorobenzene; for 14h; Inert atmosphere; Reflux;

DOI:10.1021/ja108865w

Reference yield:

→ Isopeperine (30511-76-3,7780-20-3)

Guidance literature:

1e, Piperidin (ueber d. Saeurechlorid);

upstream raw materials:

Piperine