H-Lys-OBzl p-tosylate

Base Information

• Chemical Name: H-Lys-OBzl p-tosylate
• CAS No.: 16259-78-2
• Molecular Formula: C27H36N2O8S2
• Molecular Weight: 580.723
• European Community (EC) Number: 240-366-0
• Mol file: 16259-78-2.mol

Synonyms:16259-78-2;H-Lys-OBzl p-tosylate;MFCD08458627;H-L-Lys-OBzl 2 TosOH;SCHEMBL20572531;SY104621;Benzyl (S)-2,6-Diaminohexanoate Bis(4-methylbenzenesulfonate)

Chemical Property of H-Lys-OBzl p-tosylate

Chemical Property:

• Vapor Pressure: 1.03E-25mmHg at 25°C
• Boiling Point: 781.4°Cat760mmHg
• Flash Point: 426.4°C
• PSA: 203.84000
• Density: g/cm³
• LogP: 7.23170
• Storage Temp.: Store at 0°C
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 10
• Exact Mass: 580.19130846
• Heavy Atom Count: 39
• Complexity: 422

Purity/Quality:

97% ^*data from raw suppliers

(S)-Benzyl2,6-diaminohexanoatebis(4-methylbenzenesulfonate) 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC=C(C=C1)COC(=O)C(CCCCN)N

Technology Process of H-Lys-OBzl p-tosylate

There total 2 articles about H-Lys-OBzl p-tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

L-lysine (56-87-1,3506-25-0) + toluene-4-sulfonic acid (104-15-4) + benzyl alcohol (100-51-6,185532-71-2) → L-lysine benzyl ester bis(p-toluenesulfonate) (16259-78-2)

Guidance literature:

In benzene; at 100 ℃; for 6h;

DOI:10.1021/ja000835+

Reference yield:

→ L-lysine benzyl ester bis(p-toluenesulfonate) (16259-78-2)

Guidance literature:

Reference yield: 88.3%

N-dodecanoyl-β-alanine (21539-56-0) + L-lysine benzyl ester bis(p-toluenesulfonate) (16259-78-2) → Nα-Nε-bis[3-(N-dodecanoyl)aminopropanoyl]-L-lysine benzyl ester (1173377-69-9)

Guidance literature:

With diethyl cyanophosphonate; triethylamine; In tetrahydrofuran; at 20 ℃; Cooling with ice;

DOI:10.1039/b818206j

upstream raw materials:

L-lysine

toluene-4-sulfonic acid

benzyl alcohol

Downstream raw materials:

N^α,N^ε-bis(hexadecanoyl)-L-lysine benzyl ester

N^α,N^ε-bis(hexadecanoyl)-N-[2-(benzyloxycarbonyl)ethyl]-L-lysinamide

Nα-Nε-bis[3-(N-octanoyl)aminopropanoyl]-L-lysine benzyl ester

Nα-Nε-didodecanoyl-L-lysine benzyl ester