11beta-Hydroxy-6alpha,11-dimethylprogesterone

Base Information

Chemical Name:11beta-Hydroxy-6alpha,11-dimethylprogesterone
CAS No.:2668-68-0
Molecular Formula:C₂₃H₃₄O₃
Molecular Weight:358.521
Hs Code.:
NSC Number:51176
UNII:1493L54DYM
DSSTox Substance ID:DTXSID301224591
Nikkaji Number:J2.793.046H
Wikidata:Q27148756
Mol file:2668-68-0.mol

Synonyms:11beta-Hydroxy-6alpha,11-dimethylprogesterone;2668-68-0;UNII-1493L54DYM;1493L54DYM;NSC 51176;NSC-51176;11beta-Hydroxy-6alpha,11-dimethylpregn-4-ene-3,20-dione;CHEBI:79634;DTXSID301224591;NSC51176;Q27148756;11.BETA.-HYDROXY-6.ALPHA.,11-DIMETHYLPROGESTERONE;Pregn-4-ene-3,20-dione, 11beta-hydroxy-6alpha,11-dimethyl-;PROGESTERONE, 11.BETA.-HYDROXY-6.ALPHA.,11-DIMETHYL-;PREGN-4-ENE-3,20-DIONE, 11.BETA.-HYDROXY-6.ALPHA.,11-DIMETHYL-

Suppliers and Price of 11beta-Hydroxy-6alpha,11-dimethylprogesterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 11beta-Hydroxy-6alpha,11-dimethylprogesterone

Chemical Property:

Vapor Pressure:8.18E-12mmHg at 25°C
Boiling Point:493.6°Cat760mmHg
Flash Point:266.4°C
PSA：54.37000
Density:1.12g/cm³
LogP:4.33040
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:358.25079494
Heavy Atom Count:26
Complexity:694

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)CC4)C)(C)O)C)C(=O)C
Isomeric SMILES:C[C@H]1C[C@H]2[C@@H]3CC[C@@H]([C@]3(C[C@]([C@@H]2[C@@]4(C1=CC(=O)CC4)C)(C)O)C)C(=O)C

Technology Process of 11beta-Hydroxy-6alpha,11-dimethylprogesterone

There total 3 articles about 11beta-Hydroxy-6alpha,11-dimethylprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112685-35-5
5,11β-dihydroxy-6β,11α-dimethyl-5α-pregnane-3,20-dione

: 2668-68-0
11β-hydroxy-6β,11α-dimethyl-pregn-4-ene-3,20-dione

Guidance literature:: With sodium hydroxide; ethanol;

Reference yield:

: 2302-12-7
17-acetyl-10,13-dimethyl-1,6,7,8,9,10,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,11-dione-3,21-diethylene ketal

: 2668-68-0
11β-hydroxy-6β,11α-dimethyl-pregn-4-ene-3,20-dione

Guidance literature:: Multi-step reaction with 3 steps

1: chloroform; sodium acetate; peroxyacetic acid

2: THF; diethyl ether / Erwaermen des Reaktionsprodukts in Aceton mit wss.H₂SO₄

3: ethanol; aq. NaOH solution

With tetrahydrofuran; peracetic acid; sodium hydroxide; diethyl ether; ethanol; chloroform; sodium acetate;

Reference yield:

: 54690-56-1
3,3;20,20-bis-ethanediyldioxy-5,6α-epoxy-5α-pregnan-11-one

: 2668-68-0
11β-hydroxy-6β,11α-dimethyl-pregn-4-ene-3,20-dione

Guidance literature:: Multi-step reaction with 2 steps

1: THF; diethyl ether / Erwaermen des Reaktionsprodukts in Aceton mit wss.H₂SO₄

2: ethanol; aq. NaOH solution

With tetrahydrofuran; sodium hydroxide; diethyl ether; ethanol;