5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one

Base Information

Chemical Name:5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one
CAS No.:62762-78-1
Molecular Formula:C₁₆H₁₃NO₂
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID20492721
Wikidata:Q82338857

Synonyms:62762-78-1;5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one;DTXSID20492721

Suppliers and Price of 5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:374

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=C(NC(=O)O2)C3=CC=CC=C3

Technology Process of 5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one

There total 4 articles about 5-(4-Methylphenyl)-4-phenyl-1,3-oxazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 89848-96-4
(2S,3R)-2-Phenyl-3-p-tolyl-oxirane-2-carbonyl azide

: 62762-78-1
4-Phenyl-5-p-tolyl-oxazol-2-on

Guidance literature:: In tetrachloromethane; for 5h; Heating;
DOI:10.1021/jo00186a030

Reference yield:

: 89848-82-8
(2R,3S)-2-Phenyl-3-p-tolyl-oxirane-2-carbonyl chloride

: 62762-78-1
4-Phenyl-5-p-tolyl-oxazol-2-on

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazoic acid, pyridine / diethyl ether; benzene / 1 h / -20 to 10 deg C

2: 57 percent / CCl₄ / 5 h / Heating

With pyridine; hydrogen azide; In tetrachloromethane; diethyl ether; benzene;
DOI:10.1021/jo00186a030

Reference yield:

: 89848-69-1
Sodium; (2R,3S)-2-phenyl-3-p-tolyl-oxirane-2-carboxylate

: 62762-78-1
4-Phenyl-5-p-tolyl-oxazol-2-on

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl chloride, pyridine / tetrahydrofuran / 1 h / Ambient temperature

2: hydrazoic acid, pyridine / diethyl ether; benzene / 1 h / -20 to 10 deg C

3: 57 percent / CCl₄ / 5 h / Heating

With pyridine; hydrogen azide; oxalyl dichloride; In tetrahydrofuran; tetrachloromethane; diethyl ether; benzene;
DOI:10.1021/jo00186a030