3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one

Base Information

Chemical Name:3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one
CAS No.:62787-40-0
Molecular Formula:C18H18N2O3
Molecular Weight:310.353
Hs Code.:
DSSTox Substance ID:DTXSID30561093
Wikidata:Q82444751

Synonyms:62787-40-0;3-(3,4-Dimethoxyphenethyl)quinazolin-4(3H)-one;3-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dihydroquinazolin-4-one;3-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4-one;3-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4(3H)-one;DTXSID30561093;AKOS022117145

Suppliers and Price of 3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:310.13174244
Heavy Atom Count:23
Complexity:440

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CCN2C=NC3=CC=CC=C3C2=O)OC

Technology Process of 3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one

There total 9 articles about 3-[2-(3,4-Dimethoxyphenyl)ethyl]quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 125232-06-6
2-Amino-N-<β-(3,4-dimethoxyphenyl)ethyl>benzamide

: 122-51-0
orthoformic acid triethyl ester

: 62787-40-0
3-<β-(3,4-Dimethoxyphenyl)ethyl>-3,4-dihydro-4(3H)-oxoquinazoline

Guidance literature:: for 12h; Reflux;
DOI:10.3390/molecules19078725

Reference yield:

: 552-16-9,104810-18-6
ortho-nitrobenzoic acid

: 62787-40-0
3-<β-(3,4-Dimethoxyphenyl)ethyl>-3,4-dihydro-4(3H)-oxoquinazoline

Guidance literature:: Multi-step reaction with 4 steps

1: PCl₅ / a. RT, 20min; b. reflux, 1.5h

2: benzene / 0.75 h / Ambient temperature

3: 55.6 percent / FeSO₄*7H₂O, NH₄OH / H₂O / 3 h / Heating

4: 43.7 percent / 6 h / 154 °C

With ammonium hydroxide; phosphorus pentachloride; iron(II) sulfate; In water; benzene;

Reference yield:

: 4230-93-7
1,2-dimethoxy-4-(2-nitro-vinyl)-benzene

: 62787-40-0
3-<β-(3,4-Dimethoxyphenyl)ethyl>-3,4-dihydro-4(3H)-oxoquinazoline

Guidance literature:: Multi-step reaction with 4 steps

1: LAH

2: benzene / 0.75 h / Ambient temperature

3: 55.6 percent / FeSO₄*7H₂O, NH₄OH / H₂O / 3 h / Heating

4: 43.7 percent / 6 h / 154 °C

With ammonium hydroxide; lithium aluminium tetrahydride; iron(II) sulfate; In water; benzene;