4-Phenoxy-2,3-dihydro-1H-inden-1-one

Base Information

Chemical Name:4-Phenoxy-2,3-dihydro-1H-inden-1-one
CAS No.:62803-52-5
Molecular Formula:C15H12O2
Molecular Weight:224.259
Hs Code.:
DSSTox Substance ID:DTXSID80498305
Wikidata:Q82348284

Synonyms:62803-52-5;4-Phenoxy-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 2,3-dihydro-4-phenoxy-;4-phenoxy-2,3-dihydroinden-1-one;SCHEMBL3628910;DTXSID80498305;XUAFOJPRPWYVAM-UHFFFAOYSA-N;A1-28311

Suppliers and Price of 4-Phenoxy-2,3-dihydro-1H-inden-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Phenoxy-2,3-dihydro-1H-inden-1-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:224.083729621
Heavy Atom Count:17
Complexity:281

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)C2=C1C(=CC=C2)OC3=CC=CC=C3

Technology Process of 4-Phenoxy-2,3-dihydro-1H-inden-1-one

There total 1 articles about 4-Phenoxy-2,3-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40731-98-4
4-hydroxy-2,3-dihydroindan-1-one

: 1483-72-3
diphenyliodonium chloride

: 62803-52-5
4-phenoxy-2,3-dihydroinden-1-one

Guidance literature:: With sodium hydroxide;

Reference yield:

: 62803-52-5
4-phenoxy-2,3-dihydroinden-1-one

: 68634-00-4
4-phenoxy-2,3-dihydro-1H-inden-1-ol

Guidance literature:: With sodium tetrahydroborate; In methanol;

Reference yield:

: 62803-52-5
4-phenoxy-2,3-dihydroinden-1-one

: N-Acetoxy-N-(7-phenoxy-1H-inden-2-ylmethyl)-acetamide

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) BF₃*Et₂O, 2.) N,N-diisopropylethylamine / 1.) CH₂Cl₂, 0 deg C, 2.) CH₂Cl₂, from -78 to -10 deg C

2: NaBH₄ / methanol / 0 °C

3: 2N aq. HCl / dioxane / 70 °C

4: 100 percent / NaBH₄ / methanol; tetrahydrofuran / 0.17 h / 0 °C

5: 93.9 percent / 48percent aq. HBr / diethyl ether; hexane / 1 h / 0 - 20 °C

6: 95 percent / K₂CO₃ / dimethylformamide / Ambient temperature

7: 73.6 percent / conc. HCl / methanol / 6.5 h / 0 - 20 °C

8: pyridine / CH₂Cl₂ / 1.5 h / Ambient temperature

With pyridine; hydrogenchloride; sodium tetrahydroborate; boron trifluoride diethyl etherate; hydrogen bromide; potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.46.966