(2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone

Base Information

• Chemical Name: (2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone
• CAS No.: 62810-56-4
• Molecular Formula: C13H8Cl2O2
• Molecular Weight: 267.10700
• DSSTox Substance ID: DTXSID00505303

Synonyms:62810-56-4;(2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone;DTXSID00505303

Chemical Property of (2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone

Chemical Property:

• PSA: 37.30000
• LogP: 3.93000
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 265.9901349
• Heavy Atom Count: 17
• Complexity: 283

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)O)C(=O)C2=C(C=C(C=C2)Cl)Cl

Technology Process of (2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone

There total 2 articles about (2,4-Dichlorophenyl)(3-hydroxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

m-anisoyl chloride (1711-05-3) + 1,3-Dichlorobenzene (541-73-1) → (2,4-Dichloro-phenyl)-(3-hydroxy-phenyl)-methanone (62810-56-4)

Guidance literature:

With aluminium trichloride; 1.) room temp., 1.5 h, 2.) reflux, 2 h;

Reference yield:

3-methoxyphenyl bromide (2398-37-0) + 3,5-dichlorobenzoic acid sodium salt → (2,4-Dichloro-phenyl)-(3-hydroxy-phenyl)-methanone (62810-56-4)

Guidance literature:

Multistep reaction; (i) nBuLi, (ii) /BRN= 6304798/, (iii) (demethylation);

Reference yield: 90.0%

(2,4-Dichloro-phenyl)-(3-hydroxy-phenyl)-methanone (62810-56-4) + Ethyl 2-bromopropionate (535-11-5,41978-69-2) → 2-[3-(2,4-Dichloro-benzoyl)-phenoxy]-propionic acid ethyl ester (74167-93-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

upstream raw materials:

3-methoxyphenyl bromide

m-anisoyl chloride

1,3-Dichlorobenzene

Downstream raw materials:

2-[3-(2,4-Dichloro-benzoyl)-phenoxy]-propionic acid ethyl ester

2-[3-(2,4-dichlorobenzoyl)-phenoxy]-propionic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 62810-56-4 Methanone, (2,4-dichlorophenyl)(3-hydroxyphenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send