N-(2-chlorophenyl)-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-(2-chlorophenyl)-2,2,2-trifluoroacetamide
CAS No.:62926-91-4
Molecular Formula:C8H5ClF3NO
Molecular Weight:223.582
Hs Code.:
DSSTox Substance ID:DTXSID70402991
Nikkaji Number:J2.328.037J
Wikidata:Q82206524

Synonyms:N-(2-chlorophenyl)-2,2,2-trifluoroacetamide;62926-91-4;ST51016430;Acetamide, N-(2-chlorophenyl)-2,2,2-trifluoro-;SCHEMBL5551534;DTXSID70402991;PVXHGQMYBCEHRD-UHFFFAOYSA-N;AKOS003107521;3-amino-N-(2,6-difluorobenzyl)benzamide;EN300-1704180;865814-72-8

Suppliers and Price of N-(2-chlorophenyl)-2,2,2-trifluoroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-chlorophenyl)-2,2,2-trifluoroacetamide

Chemical Property:

PSA：32.59000
LogP:3.49030
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:223.0011760
Heavy Atom Count:14
Complexity:219

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)NC(=O)C(F)(F)F)Cl

Technology Process of N-(2-chlorophenyl)-2,2,2-trifluoroacetamide

There total 2 articles about N-(2-chlorophenyl)-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 95-51-2
o-chloroaniline

: 407-25-0
trifluoroacetic anhydride

: 62926-91-4
N-(2-chlorophenyl)-2,2,2-trifluoro-acetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 0.75h;
DOI:10.1021/acs.jmedchem.7b00443

Reference yield: 89.0%

: 95-51-2
o-chloroaniline

: 76-05-1
trifluoroacetic acid

: 62926-91-4
N-(2-chlorophenyl)-2,2,2-trifluoro-acetamide

Guidance literature:: In 5,5-dimethyl-1,3-cyclohexadiene; for 3.5h; Reflux;
DOI:10.1016/j.tetlet.2009.01.088

Reference yield: 98.0%

: 62926-91-4
N-(2-chlorophenyl)-2,2,2-trifluoro-acetamide

: 108-95-2,27073-41-2
phenol

: 311764-69-9
2,2,2-trifluoro-N-(2-phenoxyphenyl)acetamide

Guidance literature:: With dimethylaminoacetic acid; caesium carbonate; potassium iodide; copper(I) bromide; In dimethyl sulfoxide; at 90 ℃; for 11h; Inert atmosphere;
DOI:10.1002/cjoc.201090279