6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride

Base Information

• Chemical Name: 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride
• CAS No.: 41372-20-7
• Molecular Formula: C17H17NO2.ClH.1/2H2O
• Molecular Weight: 624.21
• Hs Code.: 2933997000
• NSC Number: 755875
• DSSTox Substance ID: DTXSID10961395
• ChEMBL ID: CHEMBL1315821
• Mol file: 41372-20-7.mol

Synonyms:41035-30-7;S(+)-10,11-dihydroxyaporphine;S(+)-APO hydrochloride;(R)-Apomorphine-d3Hydrochloride;(R)-ApoMorphine-d4 Hydrochloride;s(+)-Apomorphine hydrochloride hydrate;C17H17NO2.ClH;SR-01000076239;(S)-(+)-Apomorphine hydrochloride;C17H17NO2.ClH.1/2H2O;C17-H17-N-O2.Cl-H.1/2H2-O;SPECTRUM1500129;SCHEMBL5904190;CHEMBL1315821;DTXSID10961395;(S)-(+)-Apomorphinehydrochloride;HMS1920E11;Pharmakon1600-01500129;(S)-(+)-APOMORPHINE HCL;Tox21_500076;CCG-38941;NSC755875;AKOS015962066;S(+)-APOMORPHINE HYDROCHLORIDE;LP00076;NCGC00093584-01;NCGC00093584-02;NCGC00093584-03;NCGC00260761-01;EU-0100076;A 4393;10,11-Dihydroxyaporphine hydrochloride hemihydrate;SR-01000076239-1;6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride;4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aS)-;6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol--hydrogen chloride (1/1)

Chemical Property of 6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride

Chemical Property:

• Appearance/Colour: grey crystalline powder
• Vapor Pressure: 1.38E-09mmHg at 25°C
• Melting Point: 285-287 °C(lit.)
• Boiling Point: 473.4 °C at 760 mmHg
• Flash Point: 268.8 °C
• PSA: 52.93000
• Density: 1.299 g/cm3
• LogP: 3.52550
• Storage Temp.: Refrigerator
• Solubility.: H2O: ~10 mg/mL, clear, yellow-green
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 303.1026065
• Heavy Atom Count: 21
• Complexity: 374

Purity/Quality:

98%,99%, ^*data from raw suppliers

R-(?)-Apomorphine hydrochloride hemihydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.Cl
• Description: Apomorphine (41372-20-7) is an archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo.1 Protects against MPTP-induced neurotoxicity in a mouse mode1,2 In clinical use for Parkinson’s disease.4,5
• Uses: emetic, antiparkinsonian, erextile dysfunction therapy Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. R-(?)-Apomorphine hydrochloride hemihydrate is a nonselective dopamine agonist with anti-Parkinsonian and neuroprotective effects in vivo.