2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid

Base Information

Chemical Name:2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid
CAS No.:142259-95-8
Molecular Formula:C19H24 O3 S
Molecular Weight:332.4571
Hs Code.:
DSSTox Substance ID:DTXSID60161989
Nikkaji Number:J491.856H
Wikidata:Q83030480
ChEMBL ID:CHEMBL321406
Mol file:142259-95-8.mol

Synonyms:2-((4-(5-(3-phenylpropyl)-2-thienyl)butyl)oxy)acetic acid;RP 64966;RP 64966, sodium salt;RP-64966

Suppliers and Price of 2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid

Chemical Property:

Vapor Pressure:3.43E-11mmHg at 25°C
Boiling Point:509.2°Cat760mmHg
Flash Point:261.8°C
Density:1.151g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:11
Exact Mass:332.14461580
Heavy Atom Count:23
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCCC2=CC=C(S2)CCCCOCC(=O)O

Technology Process of 2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid

There total 5 articles about 2-((4-(5-(3-Phenylpropyl)-2-thienyl)butyl)oxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91950-17-3
ethyl 4-(thiophen-2-yl)butanoate

: 142259-95-8
2-<<4-<5-(3-phenylpropyl)-2-thienyl>butyl>oxy>acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: SnCl₄ / tetrahydrofuran

2: NH₂NH₂*H₂O, KOH / various solvent(s) / 4 h / 210 °C

3: 80 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

4: potassium tert-butoxide / 2-methyl-propan-2-ol / 16 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; potassium tert-butylate; tin(IV) chloride; hydrazine hydrate; In tetrahydrofuran; tert-butyl alcohol;
DOI:10.1021/jm00095a010

Reference yield:

: 142260-66-0
4-<5-(3-phenylpropyl)-2-thienyl>butanoic acid

: 142259-95-8
2-<<4-<5-(3-phenylpropyl)-2-thienyl>butyl>oxy>acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

2: potassium tert-butoxide / 2-methyl-propan-2-ol / 16 h / Heating

With lithium aluminium tetrahydride; potassium tert-butylate; In tetrahydrofuran; tert-butyl alcohol;
DOI:10.1021/jm00095a010

Reference yield:

: 148111-78-8
4-[5-(3-Phenyl-propionyl)-thiophen-2-yl]-butyric acid ethyl ester

: 142259-95-8
2-<<4-<5-(3-phenylpropyl)-2-thienyl>butyl>oxy>acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: NH₂NH₂*H₂O, KOH / various solvent(s) / 4 h / 210 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / 1 h / Ambient temperature

3: potassium tert-butoxide / 2-methyl-propan-2-ol / 16 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; potassium tert-butylate; hydrazine hydrate; In tetrahydrofuran; tert-butyl alcohol;
DOI:10.1021/jm00095a010