3-Amino-2-(p-tolyl)quinazolin-4(3H)-one

Base Information

Chemical Name:3-Amino-2-(p-tolyl)quinazolin-4(3H)-one
CAS No.:63002-95-9
Molecular Formula:C15H13N3O
Molecular Weight:251.288
Hs Code.:
DSSTox Substance ID:DTXSID401322166
ChEMBL ID:CHEMBL1881455

Synonyms:3-Amino-2-(p-tolyl)quinazolin-4(3H)-one;63002-95-9;3-Amino-2-p-tolyl-3H-quinazolin-4-one;3-amino-2-(4-methylphenyl)quinazolin-4(3H)-one;3-amino-2-(4-methylphenyl)-3,4-dihydroquinazolin-4-one;3-AMINO-2-P-TOLYLQUINAZOLIN-4(3H)-ONE;3-amino-2-(4-methylphenyl)quinazolin-4-one;Cambridge id 6752704;Oprea1_380256;MLS001185445;CHEMBL1881455;SCHEMBL20102622;DTXSID401322166;HMS2825L12;STK036988;AKOS000299457;SMR000502118;BB 0244840;CS-0331547;AB00118234-01

Suppliers and Price of 3-Amino-2-(p-tolyl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-Amino-2-(p-tolyl)quinazolin-4(3H)-one

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:251.105862047
Heavy Atom Count:19
Complexity:385

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=O)N2N

Technology Process of 3-Amino-2-(p-tolyl)quinazolin-4(3H)-one

There total 7 articles about 3-Amino-2-(p-tolyl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 18600-54-9
2-(4-methylphenyl)-4H-3,1-benzoxazin-4-one

: 63002-95-9
3-amino-2-(4-methylphenyl)quinazolin-4(3H)-one

Guidance literature:: With hydrazine hydrate; In xylene; for 2h; Heating; further solvent: pyridine;

Reference yield: 67.0%

: 35709-65-0
2-(4-methylbenzoylamino)benzoylhydrazine

: 63002-95-9
3-amino-2-(4-methylphenyl)quinazolin-4(3H)-one

Guidance literature:: In pyridine; for 2h; Heating;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 63002-95-9
3-amino-2-(4-methylphenyl)quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / toluene / 6 h / 20 °C

2: acetic anhydride / 3 h / Reflux

3: hydrazine hydrate / neat (no solvent) / 1 h / 200 °C

With pyridine; hydrazine hydrate; acetic anhydride; In toluene;
DOI:10.1002/ardp.201400065