16,28-Secosolanida-5,22(28)-diene-3β,16α-diol

Base Information

Chemical Name:16,28-Secosolanida-5,22(28)-diene-3β,16α-diol
CAS No.:29271-49-6
Molecular Formula:C₂₇H₄₃NO₂
Molecular Weight:413.644
Hs Code.:

Synonyms:16,28-Secosolanida-5,22(28)-diene-3,16-diol,(3b,16a)-; Pregn-5-ene-3b,16a-diol, 20a-[(5S)-3,4,5,6-tetrahydro-5-methyl-2-pyridyl]-(8CI); Deoxoveralodisinol; Etioline; Veralosidine

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 16,28-Secosolanida-5,22(28)-diene-3β,16α-diol

Chemical Property:

Vapor Pressure:3.99E-14mmHg at 25°C
Boiling Point:544.5°Cat760mmHg
Flash Point:367.4°C
PSA：52.82000
Density:1.25g/cm³
LogP:4.83970

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description A cholestanol type alkaloid present in Veratrum album subsp. lobelianum, this base occurs primarily in the aerial parts of the plant. The structure has been determined as 22: 26-epiminocholesta-5: 22(N)-diene-3β: 16a-diol.

Technology Process of 16,28-Secosolanida-5,22(28)-diene-3β,16α-diol

There total 11 articles about 16,28-Secosolanida-5,22(28)-diene-3β,16α-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 129938-52-9
(22R,25S)-N-Chloro-22,26-epiminocholest-5-ene-3β,16α-diol

: 29271-49-6,36067-58-0
Etioline

Guidance literature:: With sodium methylate; In methanol; for 2h; Heating;

Reference yield: 12.0%

: 4847-09-0,129850-55-1,129938-49-4,129938-51-8,129938-52-9
(3S,8S,9S,10R,13S,14S,17R)-17-[(S)-1-((2S,5S)-1-Chloro-5-methyl-piperidin-2-yl)-ethyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,16-diol

: 29271-49-6,36067-58-0
Etioline

: 65027-01-2
deacetylmuldamine

: 546-40-7
(25S)-3β-hydroxy-22βN-spirosol-5-ene

Guidance literature:: With sodium methylate; In methanol; for 2h; Heating;

Reference yield:

: 1176-36-9,6785-55-3,35410-24-3,36456-16-3,65027-00-1,65027-01-2,68422-03-7,96391-23-0,123123-41-1
(3S,8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-17-[(S)-1-((2S,5S)-5-methyl-piperidin-2-yl)-ethyl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,16-diol

: 29271-49-6,36067-58-0
Etioline

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / N-chlorosuccinimide / CHCl₃ / 0.5 h / Ambient temperature

2: 28 percent / NaOMe / methanol / 2 h / Heating

With N-chloro-succinimide; sodium methylate; In methanol; chloroform;