2-Amino-2-butylhexanoic acid

Base Information

• Chemical Name: 2-Amino-2-butylhexanoic acid
• CAS No.: 7597-66-2
• Molecular Formula: C10H21NO2
• Molecular Weight: 187.282
• Hs Code.: 2922499990
• NSC Number: 42318
• DSSTox Substance ID: DTXSID50226874
• Nikkaji Number: J617.296B
• Mol file: 7597-66-2.mol

Synonyms:2-butylnorleucine;alpha,alpha-di-n-butylglycine

Chemical Property of 2-Amino-2-butylhexanoic acid

Chemical Property:

• Vapor Pressure: 0.000386mmHg at 25°C
• Refractive Index: 1.468
• Boiling Point: 294.8 °C at 760 mmHg
• Flash Point: 132.1 °C
• PSA: 63.32000
• Density: 0.975 g/cm³
• LogP: 2.84920
• Storage Temp.: Store at RT.
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 187.157228913
• Heavy Atom Count: 13
• Complexity: 149

Purity/Quality:

97% ^*data from raw suppliers

5-Aminononane-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC(CCCC)(C(=O)O)N
• Uses: 5-Aminononane-5-carboxylic Acid is a reagent used in the synthesis of Fmoc-α-?dialkylamino acids.

Technology Process of 2-Amino-2-butylhexanoic acid

There total 3 articles about 2-Amino-2-butylhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,5-di-(n-butyl)imidazolidine-2,4-dione (7148-46-1) → Cα,α-Di-n-butylglycin (7597-66-2)

Guidance literature:

(hydrolysis);

DOI:10.1021/jm00273a004

Reference yield:

2-amino-2-butyl-hexanoic acid ethyl ester (393855-78-2) → Cα,α-Di-n-butylglycin (7597-66-2)

Guidance literature:

With hydrogenchloride;

Reference yield:

N-Acetyl-Cα,α-di-n-butylglycin (130640-25-4) → Cα,α-Di-n-butylglycin (7597-66-2)

Guidance literature:

With sulfuric acid; Hydrolysis;

upstream raw materials:

2-amino-2-butyl-hexanoic acid ethyl ester

N-Acetyl-C^α,α-di-n-butylglycin

5,5-di-(n-butyl)imidazolidine-2,4-dione