4,5'-Dichloro-2'-hydroxychalcone

Base Information

• Chemical Name: 4,5'-Dichloro-2'-hydroxychalcone
• CAS No.: 36768-48-6
• Molecular Formula: C15H10Cl2O2
• Molecular Weight: 293.149
• European Community (EC) Number: 253-196-7
• NSC Number: 54883
• Nikkaji Number: J1.377.180D,J332.350A
• Metabolomics Workbench ID: 73679
• ChEMBL ID: CHEMBL2262118
• Mol file: 36768-48-6.mol

Synonyms:4,5'-Dichloro-2'-hydroxychalcone;36768-48-6;EINECS 253-196-7;2-Propen-1-one, 1-(5-chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)-;NSC54883;Chalcone, 11;(2E)-1-(5-chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one;SCHEMBL5085100;CHEMBL2262118;BDBM86012;2'-Hydroxy-4,5'-dichlorochalcone;(E)-1-(5-chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one;NSC 54883;NSC-54883;STK888325;AKOS002163858;2'-Hydroxy-4-chloro-5'-chloro-trans-chalcone;4,5'-Dichloro-2'-hydroxychalcone, AldrichCPR

Chemical Property of 4,5'-Dichloro-2'-hydroxychalcone

Chemical Property:

• Boiling Point: 469.4°Cat760mmHg
• Flash Point: 237.7°C
• Density: 1.381g/cm³
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 292.0057849
• Heavy Atom Count: 19
• Complexity: 335

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C=CC(=O)C2=C(C=CC(=C2)Cl)O)Cl
• Isomeric SMILES: C1=CC(=CC=C1/C=C/C(=O)C2=C(C=CC(=C2)Cl)O)Cl

Technology Process of 4,5'-Dichloro-2'-hydroxychalcone

There total 4 articles about 4,5'-Dichloro-2'-hydroxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-chloro-2-hydroxyacetophenone (1450-74-4) + 4-chlorobenzaldehyde (104-88-1) → (E)-1-(5-Chloro-2-hydroxy-phenyl)-3-(4-chloro-phenyl)-propenone (36768-48-6)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 20 ℃;

Reference yield: 80.0%

5-chloro-2-hydroxyacetophenone (1450-74-4) + 4-chlorobenzaldehyde (104-88-1) → (E)-1-(5-chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one (36768-48-6,126267-41-2)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 20 ℃;

Reference yield: 66.0%

5-chloro-2-hydroxyacetophenone (1450-74-4) + 4-chlorobenzaldehyde (104-88-1) → 6,4'-dichloroflavanone (6336-05-6) + (E)-1-(5-Chloro-2-hydroxy-phenyl)-3-(4-chloro-phenyl)-propenone (36768-48-6)

Guidance literature:

With potassium carbonate; at 132 ℃; for 0.05h; Microwave irradiation;

DOI:10.1016/j.tetlet.2011.07.072

upstream raw materials:

5-chloro-2-hydroxyacetophenone

4-chlorobenzaldehyde

Downstream raw materials:

(2S,3R)-6-Chloro-2-(4-chloro-phenyl)-4,4-dimethoxy-chroman-3-ol

4',6-dichloroflavan

6-chloro-2-(4-chlorophenyl)-4H-chromen-4-one

6,4'-dichloroflavanone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 36768-48-6 (E)-1-(5-chloro-2-hydroxy-phenyl)-3-(4-chlorophenyl)prop-2-en-1-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send