Propanamide, N-[3'-[[5-(aminoiminomethyl)-2-(methylthio)-3-thienyl]sulfonyl]-4-methoxy -6-methyl[1,1'-biphenyl]-2-yl]-3-(methylsulfonyl)-, mono(trifluoroacetate)

Base Information

• Chemical Name: Propanamide, N-[3'-[[5-(aminoiminomethyl)-2-(methylthio)-3-thienyl]sulfonyl]-4-methoxy -6-methyl[1,1'-biphenyl]-2-yl]-3-(methylsulfonyl)-, mono(trifluoroacetate)
• CAS No.: 631906-99-5
• Molecular Formula: C24H27N3O6S4.C2HF3O2
• Molecular Weight: 695.783

Synonyms:

Chemical Property of Propanamide, N-[3'-[[5-(aminoiminomethyl)-2-(methylthio)-3-thienyl]sulfonyl]-4-methoxy -6-methyl[1,1'-biphenyl]-2-yl]-3-(methylsulfonyl)-, mono(trifluoroacetate)

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Technology Process of Propanamide, N-[3'-[[5-(aminoiminomethyl)-2-(methylthio)-3-thienyl]sulfonyl]-4-methoxy -6-methyl[1,1'-biphenyl]-2-yl]-3-(methylsulfonyl)-, mono(trifluoroacetate)

There total 2 articles about Propanamide, N-[3'-[[5-(aminoiminomethyl)-2-(methylthio)-3-thienyl]sulfonyl]-4-methoxy -6-methyl[1,1'-biphenyl]-2-yl]-3-(methylsulfonyl)-, mono(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

→ N-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-3-sulfonyl)-4-methoxy-6-methyl-biphenyl-2-yl]-3-methanesulfonyl-propionamide trifluoroacetate (631906-99-5)

Guidance literature:

Reference yield:

2-{[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-3-sulfonyl)-2-methyl-biphenyl-4-ylcarbamoyl]-methylsulfanyl}-acetamide trifluoroacetate + {[4-(2'-Amino-4'-methoxy-6'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl-thiophen-2-yl]-imino-methyl}-carbamic acid tert-butyl ester + 5-methoxy-3-methyl-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine (631910-83-3) + acryloyl chloride (814-68-6,25189-84-8) → N-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-3-sulfonyl)-4-methoxy-6-methyl-biphenyl-2-yl]-3-methanesulfonyl-propionamide trifluoroacetate (631906-99-5)

Guidance literature:

With triethylamine; In tetrahydrofuran;

upstream raw materials:

5-methoxy-3-methyl-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine

acryloyl chloride

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