6-Epimedroxyprogesterone acetate

Base Information

Chemical Name:6-Epimedroxyprogesterone acetate
CAS No.:2242-65-1
Molecular Formula:C₂₄H₃₄O₄
Molecular Weight:386.532
Hs Code.:
European Community (EC) Number:828-560-9
NSC Number:119085
UNII:275N4RXX0Q
Nikkaji Number:J2.199.871K
Wikidata:Q27254163
Mol file:2242-65-1.mol

Synonyms:6-Epimedroxyprogesterone acetate;2242-65-1;NSC-119085;UNII-275N4RXX0Q;275N4RXX0Q;Megestrol acetate impurity F [EP];6beta-Methyl-3,20-dioxopregn-4-en-17-yl acetate;6beta-Methyl-17alpha-hydroxyprogesterone acetate;Medroxyprogesterone acetate specified impurity D [EP];[(6R,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6beta)-;epi-Medroxy Progesterone 17-Acetate;NSC119085;6-EPI-MEDROXYPROGESTERONE ACETATE [WHO-IP];MEGESTROL ACETATE IMPURITY F [EP IMPURITY];MEDROXYPROGESTERONE ACETATE IMPURITY D [WHO-IP];Q27254163;MEDROXYPROGESTERONE ACETATE IMPURITY D [EP IMPURITY];6.BETA.-METHYL-17.ALPHA.-HYDROXYPROGESTERONE ACETATE;6.BETA.-METHYL-3,20-DIOXOPREGN-4-EN-17-YL ACETATE;PREGN-4-ENE-3,20-DIONE, 17-(ACETYLOXY)-6-METHYL-, (6.BETA.)-

Suppliers and Price of 6-Epimedroxyprogesterone acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-epi-MedroxyProgesterone17-Acetate
1mg
$ 365.00

Labseeker
6β-Methyl-17α-hydroxyprogesterone acetate 95
5g
$ 1633.00

Total 18 raw suppliers

Chemical Property of 6-Epimedroxyprogesterone acetate

Chemical Property:

Vapor Pressure:5.44E-10mmHg at 25°C
Melting Point:249-254oC
Boiling Point:496.4°Cat760mmHg
Flash Point:213.2°C
PSA：60.44000
Density:1.13g/cm³
LogP:4.65520
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Very Slightly, Heated, Sonicated)
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:386.24570956
Heavy Atom Count:28
Complexity:767

Purity/Quality:

99% ^*data from raw suppliers

6-epi-MedroxyProgesterone17-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
Isomeric SMILES:C[C@@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)C
Uses The epimer of Medroxyprogesterone acetate (M203560). 6-epi-Medroxy Progesterone 17-Acetate (Megestrol Acetate EP Impurity F) is the epimer of Medroxyprogesterone acetate (M203560). Progesterone (1) impurity. Induces LEFTY expression in normal endometrium cells (2). As a derivative of Progesterone, it may assist in the modulation of ATP-induced calcium signaling in breast cancer cells (3).

Technology Process of 6-Epimedroxyprogesterone acetate

There total 5 articles about 6-Epimedroxyprogesterone acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: