2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-

Base Information

Chemical Name:2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-
CAS No.:634199-55-6
Molecular Formula:C14H19N5
Molecular Weight:257.338
Hs Code.:
DSSTox Substance ID:DTXSID80453954
Nikkaji Number:J1.962.050F
Wikidata:Q82275256

Synonyms:634199-55-6;2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-;DTXSID80453954;5-(4-Aminophenyl)-6-isobutylpyrimidine-2,4-diamine

Suppliers and Price of 2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:257.16404563
Heavy Atom Count:19
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)N

Technology Process of 2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)-

There total 9 articles about 2,4-Pyrimidinediamine, 5-(4-aminophenyl)-6-(2-methylpropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 634199-50-1
6-isobutyl-5-(4'-nitrophenyl)-pyrimidine-2,4-diamine

: 634199-55-6
5-(4'-aminophenyl)-6-isobutyl-pyrimidine-2,4-diamine

Guidance literature:: With hydrogen; nickel; In tetrahydrofuran; methanol; for 18h; under 2585.74 Torr;
DOI:10.1081/SCC-120024725

Reference yield:

: 5-methyl-2-(4-nitro-phenyl)-3-oxo-hexanenitrile

: 634199-55-6
5-(4'-aminophenyl)-6-isobutyl-pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: TMSCHN₂ / CH₂Cl₂ / 20 °C

1.2: ethanol / Heating

2.1: 95 percent / H₂ / Pd(OH)2 / methanol

With hydrogen; diazomethyl-trimethyl-silane; palladium dihydroxide; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.01.012

Reference yield:

: 555-21-5,34512-13-5,174848-08-9
4-Nitrophenylacetonitrile

: 634199-55-6
5-(4'-aminophenyl)-6-isobutyl-pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; DMAP / CH₂Cl₂ / 20 °C

2.1: TMSCHN₂ / CH₂Cl₂ / 20 °C

2.2: ethanol / Heating

3.1: 95 percent / H₂ / Pd(OH)2 / methanol

With dmap; hydrogen; triethylamine; diazomethyl-trimethyl-silane; palladium dihydroxide; In methanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.01.012