(+)-Podototarin

Base Information

• Chemical Name: (+)-Podototarin
• CAS No.: 2539-02-8
• Molecular Formula: C40H58O2
• Molecular Weight: 570.88732
• Mol file: 2539-02-8.mol

Synonyms:(4bS,4'bS)-1,1'-Diisopropyl-4b,8,8,4'b,8',8'-hexamethyl-4b,5,6,7,8,8a,9,10,4'b,5',6',7',8',8'a,9',10'-hexadecahydro-[3,3']biphenanthrenyl-2,2'-diol;

Chemical Property of (+)-Podototarin

Chemical Property:

• PSA: 40.46000
• LogP: 11.07200

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (+)-Podototarin

There total 7 articles about (+)-Podototarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

Totarol (1212475-14-3) → podototarin (2539-02-8)

Guidance literature:

With sodium hydroxide; ammonium persulfate; In pyridine; for 19h; Ambient temperature;

DOI:10.1071/CH9900681

Reference yield: 64.0%

trans-totarol (511-15-9) → C40H58O2 (1005348-41-3) + (+)-podototarin (2539-02-8)

Guidance literature:

With Tramates pubescens laccase; In acetate buffer; acetone; at 30 ℃; for 24h; pH=4.5; Further Variations:; Solvents; Temperatures; pH-values; Catalysts; buffer concentration; Product distribution; Enzymatic reaction;

DOI:10.1002/adsc.200700005

Reference yield: 45.0%

trans-totarol (511-15-9) → (+)-podototarin (2539-02-8)

Guidance literature:

With potassium hydroxide; potassium hexacyanoferrate(III); In water; benzene; at 20 - 100 ℃; for 1.66667h;

DOI:10.1016/j.tetasy.2007.11.024

upstream raw materials:

trans-totarol

Totarol

Refernces

• 1、 Cambie. "". . p. 391,396. Retrieved 1966.
• 2、 Gambie, Richard C.,Larsen, David S.,Rutledge, Peter S.,Woodgate, Paul D.. "Iodination of Thallium(I) salts of Phenols". . p. 767 - 769. Retrieved 2007/10/03.