N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide

Base Information

Chemical Name:N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide
CAS No.:63565-17-3
Molecular Formula:C13H11ClN2O2
Molecular Weight:262.696
Hs Code.:
DSSTox Substance ID:DTXSID20494280
Wikidata:Q82341514

Synonyms:N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide;63565-17-3;Oprea1_300024;SCHEMBL23675471;DTXSID20494280;AKOS000188033

Suppliers and Price of N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:262.0509053
Heavy Atom Count:18
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N)NC(=O)C2=C(C=CC(=C2)Cl)O

Technology Process of N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide

There total 3 articles about N-(4-Aminophenyl)-5-chloro-2-hydroxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 4638-49-7
5-chloro-2-hydroxy-N-(4-nitrophenyl)benzamide

: 63565-17-3
N-(4-aminophenyl)-5-chloro-2-hydroxybenzamide

Guidance literature:: With ammonium chloride; zinc; In methanol; water; at 0 - 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.0c01226

Reference yield:

: 321-14-2
5-chloro-2-hydroxybenzoic acid

: 106-50-3
1,4-phenylenediamine

: 63565-17-3
N-(4-aminophenyl)-5-chloro-2-hydroxybenzamide

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;
DOI:10.1007/s00044-019-02292-x