4-Iodo-n-phenylbenzamide

Base Information

• Chemical Name: 4-Iodo-n-phenylbenzamide
• CAS No.: 17370-92-2
• Molecular Formula: C13H10INO
• Molecular Weight: 323.133
• NSC Number: 136968
• DSSTox Substance ID: DTXSID10300427
• Nikkaji Number: J3.254.208E
• Wikidata: Q82043467
• Mol file: 17370-92-2.mol

Synonyms:17370-92-2;4-iodo-n-phenylbenzamide;NSC136968;SCHEMBL5718666;DTXSID10300427;AKOS001227894;NSC-136968;Z27782649

Chemical Property of 4-Iodo-n-phenylbenzamide

Chemical Property:

• Vapor Pressure: 0.000283mmHg at 25°C
• Boiling Point: 322.2°C at 760 mmHg
• Flash Point: 148.7°C
• Density: 1.697g/cm³
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 322.98071
• Heavy Atom Count: 16
• Complexity: 230

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)I

Technology Process of 4-Iodo-n-phenylbenzamide

There total 4 articles about 4-Iodo-n-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

iodobenzene (591-50-4) + 4-iodobenzamide (3956-07-8) → 4-iodo-N-phenylbenzamide (17370-92-2)

Guidance literature:

With copper(I) thiophene-2-carboxylate; sodium t-butanolate; In dimethyl sulfoxide; at 100 ℃; for 6h; Inert atmosphere;

DOI:10.1002/aoc.3080

Reference yield: 61.0%

4-iodobenzonitrile (3058-39-7) + phenylboronic acid (98-80-6) → 4-iodo-N-phenylbenzamide (17370-92-2)

Guidance literature:

With potassium tert-butylate; copper(ll) bromide; In tert-butyl alcohol; at 20 ℃; for 28h;

DOI:10.1055/s-0036-1588373

Reference yield: 40.0%

C13H9ClINO (462068-70-8) → N-phenyl benzoyl amide (93-98-1,5705-51-1) + 4-iodo-N-phenylbenzamide (17370-92-2)

Guidance literature:

With 1-[2-(N-(3-diphenylphosphinopropyl))aminoethyl]pyrrolidine; triethylamine; palladium dichloride; In water; at 100 ℃; for 12h; regioselective reaction;

DOI:10.1055/s-0040-1707116

upstream raw materials:

aniline

4-iodobenzoic acid chloride

iodobenzene

4-iodobenzamide

Downstream raw materials:

4-amino-benzoic acid anilide

4-benzamido-N-phenylbenzamide

4-acetamido-N-phenylbenzamide

2-(4-iodophenyl)benzo[d]thiazole