1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester

Base Information

Chemical Name:1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester
CAS No.:78667-03-5
Molecular Formula:C25H29ClN2O4
Molecular Weight:456.969
Hs Code.:
UNII:GN010LC6LS
DSSTox Substance ID:DTXSID60229230
Nikkaji Number:J681.483B
Wikidata:Q83109442
ChEMBL ID:CHEMBL2262719

Synonyms:78667-03-5;1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester;GN010LC6LS;Indomethacin diethylamino ethyl ester;2-(Diethylamino)ethyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate;UNII-GN010LC6LS;C25H29ClN2O4;SCHEMBL3810907;CHEMBL2262719;DTXSID60229230;LS-82128;1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid 2-(diethylamino)ethyl ester;2-diethylaminoethyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h -indole-3-acetate

Suppliers and Price of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester

Chemical Property:

Vapor Pressure:1.34E-11mmHg at 25°C
Boiling Point:536.9°Cat760mmHg
Flash Point:278.5°C
Density:1.18g/cm³
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:456.1815851
Heavy Atom Count:32
Complexity:621

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCOC(=O)CC1=C(N(C2=C1C=C(C=C2)OC)C(=O)C3=CC=C(C=C3)Cl)C

Technology Process of 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester

There total 2 articles about 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-(diethylamino)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 78667-02-4
O-(2-diethylamino-ethyl)-N,N'-diisopropyl-isourea

: 53-86-1
[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

: 78667-03-5
1-(4-Chlorbenzoyl)-5-methoxy-2-methyl-3-indolylessigsaeure-(2-diethylamino)ethylester

Guidance literature:: In benzene; for 20h; Heating;

Reference yield: 67.0%

: 53-86-1
[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

: 100-37-8
2-(Diethylamino)ethanol

: 78667-03-5
1-(4-Chlorbenzoyl)-5-methoxy-2-methyl-3-indolylessigsaeure-(2-diethylamino)ethylester

Guidance literature:: With thionyl chloride; sodium hydrogencarbonate; potassium iodide; tetraethylammonium bromide; In chloroform; water;
DOI:10.1007/s00044-007-9013-z