4-Morpholinesulfonamide

Base Information

• Chemical Name: 4-Morpholinesulfonamide
• CAS No.: 25999-04-6
• Molecular Formula: C4H10 N2 O3 S
• Molecular Weight: 166.201
• Hs Code.: 2935009090
• European Community (EC) Number: 854-177-1
• NSC Number: 125081
• DSSTox Substance ID: DTXSID10298658
• Wikidata: Q82040596
• Mol file: 25999-04-6.mol

Synonyms:morpholine-4-sulfonamide;4-Morpholinesulfonamide;25999-04-6;4-morpholine sulfonamide;morpholinosulfonamide;NSC125081;morpholinosulfonylamine;Morpholin-4-ylsulfonamide;SCHEMBL490315;morpholine-4-sulfonic acid amide;DTXSID10298658;WZWQJRQCWCFUTM-UHFFFAOYSA-N;MFCD11171673;AKOS009161153;NSC-125081;SB21418;AS-53266;CS-0048862;EN300-88728;P16262;Z300107782

Chemical Property of 4-Morpholinesulfonamide

Chemical Property:

• Vapor Pressure: 0.000156mmHg at 25°C
• Melting Point: 160 °C
• Boiling Point: 331.4°Cat760mmHg
• PKA: 12.30±0.20(Predicted)
• Flash Point: 154.3°C
• PSA: 81.01000
• Density: 1.46g/cm³
• LogP: 0.24110
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 166.04121336
• Heavy Atom Count: 10
• Complexity: 189

Purity/Quality:

NLT 98% ^*data from raw suppliers

morpholine-4-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1S(=O)(=O)N

Technology Process of 4-Morpholinesulfonamide

There total 7 articles about 4-Morpholinesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Boc-morpholine-4-sulfonic acid amide (861397-54-8) → N-sulfamoylmorpholine (25999-04-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;

Reference yield: 97.0%

benzyl (morpholin-4-ylsulfonyl)carbamate (1048017-38-4) → N-sulfamoylmorpholine (25999-04-6)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; ethanol; at 20 ℃; for 4h; under 760.051 Torr;

Reference yield: 97.0%

→ N-sulfamoylmorpholine (25999-04-6)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 3h;

upstream raw materials:

morpholine

4-nitrophenyl sulfamate

Boc-morpholine-4-sulfonic acid amide

benzyl (morpholin-4-ylsulfonyl)carbamate

Downstream raw materials:

N-(morpholine-4-sulfonyl)-benzamidine

4-Phenylmorpholine

Morpholine-4-sulfonic acid phenylamide

Morpholine-4-sulfonic acid (2-nitro-phenyl)-amide