Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl-

Base Information

• Chemical Name: Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl-
• CAS No.: 63805-63-0
• Molecular Formula: C11H18O2
• Molecular Weight: 182.25900
• Mol file: 63805-63-0.mol

Synonyms:Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl-;

Chemical Property of Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl-

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 75.4 °C
• Boiling Point: 285.46oC at 760 mmHg
• PKA: 4.79±0.10(Predicted)
• Flash Point: 139.274oC
• PSA: 37.30000
• Density: 1.068g/cm3
• LogP: 2.67750

Purity/Quality:

99% ^*data from raw suppliers

(7,7-Dimethylbicyclo[2.2.1]heptan-1-yl)aceticacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl-

There total 8 articles about Bicyclo[2.2.1]heptane-1-acetic acid, 7,7-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (7,7-dimethyl-[1]norbornyl)-acetic acid (63805-63-0)

Guidance literature:

With sodium ethanolate; at 170 - 180 ℃;

DOI:10.1021/ja01267a065

Reference yield:

2-((1R)-2endo-chloro-7,7-dimethyl-[1]norbornyl)-ethanol (63805-62-9,105583-22-0) → (7,7-dimethyl-[1]norbornyl)-acetic acid (63805-63-0)

Guidance literature:

Multi-step reaction with 2 steps

1: butan-1-ol; sodium

2: CrO₃

With chromium(VI) oxide; sodium; butan-1-ol;

DOI:10.1021/ja01163a087

Reference yield:

(1R)-1-(2-acetoxy-ethyl)-2endo-chloro-7,7-dimethyl-norbornane (100521-89-9) → (7,7-dimethyl-[1]norbornyl)-acetic acid (63805-63-0)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous methanol. KOH-solution

2: butan-1-ol; sodium

3: CrO₃

With chromium(VI) oxide; potassium hydroxide; sodium; butan-1-ol;

DOI:10.1021/ja01163a087

upstream raw materials:

2-(7,7-dimethyl-[1]norbornyl)-ethanol

((1R)-2endo-chloro-7,7-dimethyl-[1]norbornyl)-acetic acid

7,7-dimethyl-1-vinylbicyclo[2.2.1]heptane

7,7-dimethyl-1-vinylbicyclo[2.2.1]heptan-2-one