Nomifensine acetate

Base Information

Chemical Name:Nomifensine acetate
CAS No.:63806-80-4
Molecular Formula:C18H20N2O
Molecular Weight:280.37
Hs Code.:
DSSTox Substance ID:DTXSID10346643

Synonyms:63806-80-4;Nomifensine acetate;N-(2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-yl)acetamide;SCHEMBL4028451;DTXSID10346643;Acetamide, N-(1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinyl)-;N-(2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinyl)acetamide #

Suppliers and Price of Nomifensine acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Nomifensine acetate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:280.157563266
Heavy Atom Count:21
Complexity:364

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=CC2=C1CN(CC2C3=CC=CC=C3)C

Technology Process of Nomifensine acetate

There total 2 articles about Nomifensine acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 108-24-7
acetic anhydride

: 24526-64-5
nomifensine

: 63806-80-4
N-(2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isochinolyl)-acetamid

Guidance literature:: DOI:10.1002/ardp.19883211015

Reference yield:

: 63806-80-4
N-(2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isochinolyl)-acetamid

Guidance literature:: Nomifensin-hydrogenmaleinat, Acetanhydrid;

Reference yield:

: 63806-80-4
N-(2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isochinolyl)-acetamid

: N-(1-Cyano-2-methyl-4-phenyl-1,2,3,4-tetrahydro-8-isochinolinyl)-acetamid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Hg(II)-EDTA, 2.) OH^(1-) / 1.) aq. EtOH, 2.) 6 h

2: H₂O

With Hg(II)-EDTA; hydroxide; In water;
DOI:10.1002/ardp.19883211015