Technology Process of (2aR,3aS)-2aβ,3,6,7,8a,8b-Hexahydro-8aβ,8bα-dihydroxy-2,2,7β-trimethyl-2H,4H-cyclopropa[c]benzo[2,1-b:3,4-b']difuran-4-one
There total 5 articles about (2aR,3aS)-2aβ,3,6,7,8a,8b-Hexahydro-8aβ,8bα-dihydroxy-2,2,7β-trimethyl-2H,4H-cyclopropa[c]benzo[2,1-b:3,4-b']difuran-4-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrafluoroboric acid;
In
1,4-dioxane; water;
DOI:10.1021/jo00208a052
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 51 percent / dicyclohexylcarbodiimide, pyridine / dimethylsulfoxide
2: 44 percent / 50percent HBF4 / dioxane; H2O
With
pyridine; tetrafluoroboric acid; dicyclohexyl-carbodiimide;
In
1,4-dioxane; water; dimethyl sulfoxide;
DOI:10.1021/jo00208a052
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 0 °C
2: (n-Bu)4NF / tetrahydrofuran / 0.17 h / 0 °C
3: 84 percent / tert-butyl hydroperoxide, Mo(CO)6, Na2HPO4 / benzene
4: 51 percent / dicyclohexylcarbodiimide, pyridine / dimethylsulfoxide
5: 44 percent / 50percent HBF4 / dioxane; H2O
With
pyridine; tert.-butylhydroperoxide; disodium hydrogenphosphate; tetrafluoroboric acid; hexacarbonyl molybdenum; tetrabutyl ammonium fluoride; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; 1,4-dioxane; water; dimethyl sulfoxide; benzene;
DOI:10.1021/jo00208a052
