4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol

Base Information

Chemical Name:4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol
CAS No.:63925-49-5
Molecular Formula:C₁₉H₂₅NO₂
Molecular Weight:299.413
Hs Code.:2922299090
DSSTox Substance ID:DTXSID00388850
Nikkaji Number:J248.145F
Wikidata:Q82184050
ChEMBL ID:CHEMBL3301906
Mol file:63925-49-5.mol

Synonyms:63925-49-5;N-Propyl-N-phenethyldopamine;CHEMBL3301906;SCHEMBL10428293;DTXSID00388850;MRIDNSCAXRTEDV-UHFFFAOYSA-N;4-{2-[(2-PHENYLETHYL)(PROPYL)AMINO]ETHYL}BENZENE-1,2-DIOL;N-phenethyl-N-propyl-3,4-dihydroxyphenethylamine

Suppliers and Price of 4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol

Chemical Property:

PSA：43.70000
LogP:3.59500
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:299.188529040
Heavy Atom Count:22
Complexity:291

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC1=CC=CC=C1)CCC2=CC(=C(C=C2)O)O

Technology Process of 4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol

There total 4 articles about 4-{2-[(2-Phenylethyl)(propyl)amino]ethyl}benzene-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(3,4-Dimethoxy-phenyl)-N-phenethyl-N-propyl-acetamide

: 63925-49-5
N-phenethyl-N-propyl-3,4-dihydroxyphenethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: BH₃*THF / tetrahydrofuran

2: aq. HI / acetic anhydride

With borane-THF; hydrogen iodide; In tetrahydrofuran; acetic anhydride;
DOI:10.1021/jm00200a003

Reference yield:

: 4876-02-2
N-(3,4-dimethoxyphenethyl)-phenyl acetamide

: 63925-49-5
N-phenethyl-N-propyl-3,4-dihydroxyphenethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

2: 57 percent / K₂CO₃ / acetone / 6 h / Heating

3: 48 percent HBr / 3 h / Heating

With lithium aluminium tetrahydride; hydrogen bromide; potassium carbonate; In tetrahydrofuran; acetone;

Reference yield:

: 63925-47-3
N-(2-phenylethyl)-2-(3,4-dimethoxyphenyl)ethylamine

: 63925-49-5
N-phenethyl-N-propyl-3,4-dihydroxyphenethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / K₂CO₃ / acetone / 6 h / Heating

2: 48 percent HBr / 3 h / Heating

With hydrogen bromide; potassium carbonate; In acetone;