3-Ethylisoxazole-4-carboxylic acid

Base Information

Chemical Name:3-Ethylisoxazole-4-carboxylic acid
CAS No.:639523-12-9
Molecular Formula:C6H7NO3
Molecular Weight:141.126
Hs Code.:2934999090
European Community (EC) Number:818-932-9

Synonyms:3-ethylisoxazole-4-carboxylic acid;639523-12-9;3-ethyl-1,2-oxazole-4-carboxylic acid;MFCD19229970;3-ethyl-4-isoxazolecarboxylic acid;SCHEMBL5272185;3-ethylisoxazole-4-carboxylicacid;GWXJFENAVVNMTA-UHFFFAOYSA-N;3-ethyl-isoxazole4-carboxylic acid;AC1772;4-Isoxazolecarboxylic acid, 3-ethyl-;AKOS006376748;CS-12056;SY036419;DB-165845;CS-0130233;EN300-226062;A923095;Z1205496373

Suppliers and Price of 3-Ethylisoxazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Ethylisoxazole-4-carboxylicAcid
2.5mg
$ 45.00

SynQuest Laboratories
3-Ethylisoxazole-4-carboxylic acid
1 g
$ 784.00

Crysdot
3-Ethylisoxazole-4-carboxylicAcid 95+%
1g
$ 329.00

Chemenu
3-Ethylisoxazole-4-carboxylicAcid 95%
1g
$ 310.00

Apolloscientific
3-Ethylisoxazole-4-carboxylicacid
1g
$ 711.00

AK Scientific
3-Ethylisoxazole-4-carboxylicacid
10g
$ 2287.00

AK Scientific
3-Ethylisoxazole-4-carboxylicacid
5g
$ 1356.00

Total 8 raw suppliers

Chemical Property of 3-Ethylisoxazole-4-carboxylic acid

Chemical Property:

Boiling Point:290.4±20.0 °C(Predicted)
PSA：63.33000
Density:1.273±0.06 g/cm3(Predicted)
LogP:0.93520
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:141.042593085
Heavy Atom Count:10
Complexity:137

Purity/Quality:

97% ^*data from raw suppliers

3-Ethylisoxazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC1=NOC=C1C(=O)O
Uses 3-Ethylisoxazole-4-carboxylic Acid is a useful reagent in the preparation of substituted spirocyclic 2-oxoindoline derivatives which are potent modulators of human IL-17 activity; beneficial in the treatment/prevention of various human ailments, including inflammatory and autoimmune disorders.

Technology Process of 3-Ethylisoxazole-4-carboxylic acid

There total 1 articles about 3-Ethylisoxazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 639523-11-8
3-ethyl-isoxazole-4-carboxylic acid ethyl ester

: 639523-12-9
3-ethyl-isoxazole-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃;

Reference yield: 100.0%

: 639523-12-9
3-ethyl-isoxazole-4-carboxylic acid

: (S)-{4-fluoro-5-[4-(methylsulfanyl)pyridin-3-yl]-1H-benzimidazol-2-yl}(4-methyl-cyclohexyl)methanamine

: 3-ethyl-N-[(S)-{4-fluoro-5-[4-(methylsulfanyl)pyridin-3-yl]-1H-benzimidazol-2-yl}(4-methylcyclohexyl)methyl]isoxazole-4-carboxamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 20 ℃; for 48h;

Reference yield: 91.0%

: 639523-12-9
3-ethyl-isoxazole-4-carboxylic acid

: (2S)-2-amino-2-(4-methylcyclohexyl)-N-{2-oxo-1-[2-(trimethylsilyl)ethoxymethyl]spiro[pyrrolo[3,2-c]pyridine-3,4‘-tetrahydropyran]-6-yl}acetamide hydrochloride

: 3-ethyl-N-[(1S)-1-(4-methylcyclohexyl)-2-oxo-2-({2-oxo-1-[2-(trimethylsilyl)ethoxymethyl]spiro[pyrrolo[3 ,2-c]pyridine-3,4‘-tetrahydropyran]-6-yl}amino)ethyl]isoxazole-4-carboxamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 17h;