Ethyl 2-(phenylamino)propanoate

Base Information

Chemical Name:Ethyl 2-(phenylamino)propanoate
CAS No.:54860-84-3
Molecular Formula:C11H15 N O2
Molecular Weight:193.246
Hs Code.:
NSC Number:165819
DSSTox Substance ID:DTXSID50304449
Nikkaji Number:J2.116.845I

Synonyms:Ethyl 2-(phenylamino)propanoate;54860-84-3;Alanine, N-phenyl-, ethyl ester;88912-03-2;Ethyl N-phenylalaninate;ethyl 2-anilinopropanoate;DL-Phenylalanine, ethyl ester;SCHEMBL8031605;DTXSID50304449;FMFDWCAQDWISCD-UHFFFAOYSA-N;MFCD00026880;NSC165819;AKOS010217600;NSC-165819;BB 0301289;EN300-24217173

Suppliers and Price of Ethyl 2-(phenylamino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 2-(phenylamino)propanoate

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Boiling Point:284.3°Cat760mmHg
Flash Point:125.7°C
Density:1.08g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:176

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)NC1=CC=CC=C1

Technology Process of Ethyl 2-(phenylamino)propanoate

There total 6 articles about Ethyl 2-(phenylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 6111-99-5
ethyl diazoalaninate

: 62-53-3
aniline

: 54860-84-3
(S)-(-)-2-phenylamino-propionic acid ethyl ester

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; (S,E)-N-benzhydryl-2-(N,N'-dicyclohexylcarbamimidoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide; In dichloromethane; at 35 ℃; for 5h; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.201308501

Reference yield: 80.0%

: 33948-36-6
2-iodocyclohex-2-en-1-one

: 91462-82-7
L-2-aminobutyric acid ethyl ester hydrochloride

: 54860-84-3
(S)-(-)-2-phenylamino-propionic acid ethyl ester

Guidance literature:: L-2-aminobutyric acid ethyl ester hydrochloride; With potassium carbonate; In ethanol; at 20 ℃; for 1h; Inert atmosphere;

2-iodocyclohex-2-en-1-one; With toluene-4-sulfonic acid; In ethanol; at 75 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.201201263

Reference yield:

: 6111-99-5
ethyl diazoalaninate

: 62-53-3
aniline

: 54860-84-3
(S)-(-)-2-phenylamino-propionic acid ethyl ester

: 99209-03-7
ethyl (R)-(+)-2-(phenylamino)propionate

Guidance literature:: With C₃₂H₃₀N₄O₄; copper(l) chloride; In dichloromethane; at 0 ℃; for 8h; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Molecular sieve;
DOI:10.1002/anie.201001686