2-(2,5-Dimethylphenoxy)acetohydrazide

Base Information

• Chemical Name: 2-(2,5-Dimethylphenoxy)acetohydrazide
• CAS No.: 103896-91-9
• Molecular Formula: C10H14 N2 O2
• Molecular Weight: 194.233
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID40366410
• Wikidata: Q82151613
• Mol file: 103896-91-9.mol

Synonyms:2-(2,5-dimethylphenoxy)acetohydrazide;103896-91-9;(2,5-Dimethyl-phenoxy)-acetic acid hydrazide;(2,5-dimethylphenoxy)acetic acid hydrazide;Oprea1_180451;DTXSID40366410;BBL015537;MFCD02288788;STK061781;AKOS000116157;VS-04961;UPCMLD0ENAT0507-1905:001;CS-0307624;EN300-03729;Z56820972

Chemical Property of 2-(2,5-Dimethylphenoxy)acetohydrazide

Chemical Property:

• Vapor Pressure: 8.12E-07mmHg at 25°C
• Boiling Point: 406.5°Cat760mmHg
• Flash Point: 199.6°C
• PSA: 64.35000
• Density: 1.128g/cm³
• LogP: 1.76330
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 194.105527694
• Heavy Atom Count: 14
• Complexity: 197

Purity/Quality:

98%min ^*data from raw suppliers

2-(2,5-Dimethylphenoxy)acetohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C)OCC(=O)NN

Technology Process of 2-(2,5-Dimethylphenoxy)acetohydrazide

There total 2 articles about 2-(2,5-Dimethylphenoxy)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.8%

2,5-Dimethyl-phenoxyessigsaeure-ethylester → 2-(2,5-dimethylphenoxy)acetohydrazide (103896-91-9)

Guidance literature:

With hydrazine hydrate; In ethanol; Reflux;

DOI:10.2174/1570180813666160805150148

Reference yield:

2,5-Dimethylphenol (95-87-4) → 2-(2,5-dimethylphenoxy)acetohydrazide (103896-91-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; potassium iodide / acetone / Reflux

2: hydrazine hydrate / ethanol / Reflux

With potassium carbonate; hydrazine hydrate; potassium iodide; In ethanol; acetone;

DOI:10.2174/1570180813666160805150148

Reference yield: 87.0%

C13H13ClN2O + 2-(2,5-dimethylphenoxy)acetohydrazide (103896-91-9) → C23H26N4O3

Guidance literature:

With triethylamine; In ethyl acetate; at 20 ℃;

upstream raw materials:

2,5-Dimethylphenol

Downstream raw materials:

(2,5-Dimethyl-phenoxy)-acetic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide

1-(2,5-dimethylphenoxymethyl)-4-phenylthiosemicarbazide

C₁₇H₁₈ClN₃O₂S

C₁₇H₁₈ClN₃O₂S

Refernces