5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Base Information

Chemical Name:5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran
CAS No.:64165-99-7
Molecular Formula:C13H14O3
Molecular Weight:218.25
Hs Code.:
DSSTox Substance ID:DTXSID50504942
Nikkaji Number:J780.377J
Wikidata:Q82359730

Synonyms:5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran;64165-99-7;1-[2-(2-hydroxypropan-2-yl)-1-benzofuran-5-yl]ethanone;Ethanone, 1-[2-(1-hydroxy-1-methylethyl)-5-benzofuranyl]-;SCHEMBL12640272;DTXSID50504942;CHEBI:201688;AKOS030597558;1-(2-(2-Hydroxypropan-2-yl)benzofuran-5-yl)ethanone;1-[2-(2-hydroxypropan-2-yl)-1-benzouran-5-yl]ethanone;1-[2-(2-Hydroxypropan-2-yl)-1-benzofuran-5-yl]ethan-1-one

Suppliers and Price of 5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:218.094294304
Heavy Atom Count:16
Complexity:285

Purity/Quality:: 99.0% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC2=C(C=C1)OC(=C2)C(C)(C)O

Technology Process of 5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

There total 6 articles about 5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 173992-10-4
3'-(3-hydroxy-3-methylbutynyl)-4'-tosyloxyacetophenone

: 64165-99-7
5-acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Guidance literature:: With potassium carbonate; In ethanol; for 1.5h; Heating;

Reference yield:

: 62615-24-1
4'-hydroxy-3'-iodoacetophenone

: 64165-99-7
5-acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / K₂CO₃ / acetone / 0.67 h / Heating

2: 90 percent / PPh₃, CuI / PdCl₂ / triethylamine; dimethylformamide / 0.8 h / 85 °C

3: 91 percent / K₂CO₃ / ethanol / 1.5 h / Heating

With copper(l) iodide; potassium carbonate; triphenylphosphine; palladium dichloride; In ethanol; triethylamine; N,N-dimethyl-formamide; acetone;

Reference yield:

: 115-19-5
2-methyl-but-3-yn-2-ol

: 64165-99-7
5-acetyl-2-(1-hydroxy-1-methylethyl)benzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / PPh₃, CuI / PdCl₂ / triethylamine; dimethylformamide / 0.8 h / 85 °C

2: 91 percent / K₂CO₃ / ethanol / 1.5 h / Heating

With copper(l) iodide; potassium carbonate; triphenylphosphine; palladium dichloride; In ethanol; triethylamine; N,N-dimethyl-formamide;