Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-

Base Information

Chemical Name:Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-
CAS No.:83357-08-8
Molecular Formula:C₂₃H₂₇NO₇
Molecular Weight:429.47
Hs Code.:
DSSTox Substance ID:DTXSID70232295
Wikidata:Q76156817

Synonyms:83357-08-8;Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-;DTXSID70232295;LS-91074

Suppliers and Price of Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-

Chemical Property:

Vapor Pressure:5.51E-21mmHg at 25°C
Boiling Point:707.1°Cat760mmHg
Flash Point:381.4°C
Density:1.35g/cm³
XLogP3:1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:429.17875220
Heavy Atom Count:31
Complexity:629

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C(=O)C2=CC(=C(C=C2)OC3C(C(C(C(O3)CO)O)O)NC(=O)C)C
Isomeric SMILES:CC1=CC=CC=C1C(=O)C2=CC(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)NC(=O)C)C

Technology Process of Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)-

There total 5 articles about Methanone, (4-((2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)oxy)-3-methylphenyl)(2-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 147029-52-5
Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[2-methyl-4-(2-methyl-benzoyl)-phenoxy]-tetrahydro-pyran-4-yl ester

: 83357-08-8
N-{(2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-[2-methyl-4-(2-methyl-benzoyl)-phenoxy]-tetrahydro-pyran-3-yl}-acetamide

Guidance literature:: With sodium methylate; In methanol; for 2h; Ambient temperature;
DOI:10.1021/jm00059a015

Reference yield:

: 41295-37-8
4-methoxy-2',3-dimethylbenzophenone

: 83357-08-8
N-{(2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-[2-methyl-4-(2-methyl-benzoyl)-phenoxy]-tetrahydro-pyran-3-yl}-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: aq. HBr, AcOH / Heating

2: 1.) NaH / 1.) DMF, CH₂Cl₂, RT, 2 h, 2.) DMF, CH₂Cl₂, 40 deg C, 3 h

3: MeONa / methanol / 2 h / Ambient temperature

With hydrogen bromide; sodium methylate; sodium hydride; acetic acid; In methanol;
DOI:10.1021/jm00059a015

Reference yield:

: 14804-31-0
2-methyl-4-bromoanisole

: 83357-08-8
N-{(2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-2-[2-methyl-4-(2-methyl-benzoyl)-phenoxy]-tetrahydro-pyran-3-yl}-acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) Mg / 1.) THF, reflux, 2.) THF, from -20 deg C to RT

2: aq. HBr, AcOH / Heating

3: 1.) NaH / 1.) DMF, CH₂Cl₂, RT, 2 h, 2.) DMF, CH₂Cl₂, 40 deg C, 3 h

4: MeONa / methanol / 2 h / Ambient temperature

With hydrogen bromide; sodium methylate; sodium hydride; magnesium; acetic acid; In methanol;
DOI:10.1021/jm00059a015