3-Fluoro-2,2-dimethylpropanoic acid

Base Information

Chemical Name:3-Fluoro-2,2-dimethylpropanoic acid
CAS No.:64241-77-6
Molecular Formula:C5H9FO2
Molecular Weight:120.124
Hs Code.:2915907098
European Community (EC) Number:838-204-4
UNII:BHR9K4XEB2
DSSTox Substance ID:DTXSID20517968
Wikidata:Q82380288

Synonyms:3-fluoro-2,2-dimethylpropanoic acid;64241-77-6;Propanoic acid, 3-fluoro-2,2-dimethyl-;MFCD17677039;3-fluoro-2,2-dimethylpropionic acid;FPIA;3-fluoro-2,2-dimethyl-propionic acid;BHR9K4XEB2;SCHEMBL1937477;DTXSID20517968;3-fluoro-2,2-dimethylpropanoicacid;AKOS006377504;CS-W005928;FD10572;DS-17174;SY114702;3-Fluoro-2 pound not2-dimethylpropanoic acid;EN300-156604;A867918;F2147-2729;Z1205495490

Suppliers and Price of 3-Fluoro-2,2-dimethylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Fluoro-2,2-dimethylpropanoicAcid
50mg
$ 45.00

Crysdot
3-Fluoro-2,2-dimethylpropanoicacid 97%
1g
$ 208.00

American Custom Chemicals Corporation
3-FLUORO-2,2-DIMETHYLPROPANOIC ACID 95.00%
5MG
$ 499.84

Ambeed
3-Fluoro-2,2-dimethylpropanoicacid 97%
10g
$ 1216.00

Ambeed
3-Fluoro-2,2-dimethylpropanoicacid 97%
5g
$ 627.00

Ambeed
3-Fluoro-2,2-dimethylpropanoicacid 97%
1g
$ 139.00

Ambeed
3-Fluoro-2,2-dimethylpropanoicacid 97%
250mg
$ 51.00

Ambeed
3-Fluoro-2,2-dimethylpropanoicacid 97%
100mg
$ 24.00

AK Scientific
3-Fluoro-2,2-dimethylpropanoicacid
1g
$ 342.00

AK Scientific
3-Fluoro-2,2-dimethylpropanoicacid
250mg
$ 172.00

Total 35 raw suppliers

Chemical Property of 3-Fluoro-2,2-dimethylpropanoic acid

Chemical Property:

Vapor Pressure:0.236mmHg at 25°C
Boiling Point:190.6oC at 760 mmHg
PKA:4.01±0.10(Predicted)
Flash Point:69.1oC
PSA：37.30000
Density:1.08g/cm3
LogP:1.06670
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:120.05865769
Heavy Atom Count:8
Complexity:98.6

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoro-2,2-dimethylpropanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CF)C(=O)O

Technology Process of 3-Fluoro-2,2-dimethylpropanoic acid

There total 7 articles about 3-Fluoro-2,2-dimethylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: benzyl 3-fluoro-2,2-dimethylpropanoate

: 64241-77-6
β-Fluoro-pivalic acid

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 15h;
DOI:10.1002/bkcs.12254

Reference yield:

: 1068560-15-5
methyl 3-fluoro-2,2-dimethylpropanoate

: 64241-77-6
β-Fluoro-pivalic acid

Guidance literature:: methyl 3-fluoro-2,2-dimethylpropanoate; With sodium hydroxide; water; In methanol; for 3h; Heating / reflux;

With hydrogenchloride; In water;

Reference yield:

: 14002-80-3
Methyl 2,2-dimethyl-3-hydroxypropionate

: 64241-77-6
β-Fluoro-pivalic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (bis-(2-methoxyethyl)amino)sulfur trufluoride / 18 h / 70 °C / Sealed tube

2: lithium hydroxide monohydrate / methanol; water; tetrahydrofuran / 20 °C

With lithium hydroxide monohydrate; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In tetrahydrofuran; methanol; water;