Synonyms:IlwensisaponinA; Mimengoside A; Verbascosaponin
The research was conducted to isolate and structurally characterize new triterpenoid glycosides from Buddlejae Flos, a Chinese crude drug used for its anti-inflammatory properties. The study successfully identified two new compounds, mimengosides A (1) and B (2), along with acteoside (3). The structures of these compounds were determined using various spectroscopic and chemical methods, including FAB-MS, IR, 13C-NMR, and 1H-NMR. The key chemicals used in the research included methanol for extraction, benzene for defatting, and various solvents for chromatography, such as MCI gel CHP-20P, Sephadex LH-20, and silica gel. The study concluded that mimengoside A (1) has a structure of 3-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→2)]-β-D-fucopyranoside of 16-dehydroxysaikogenin G, while mimengoside B (2) is a derivative of 1, likely formed during the extraction and chromatographic procedures. The findings contribute to the understanding of the chemical composition and potential therapeutic applications of Buddlejae Flos.
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