1-(Dibromomethyl)-4-fluorobenzene

Base Information

• Chemical Name: 1-(Dibromomethyl)-4-fluorobenzene
• CAS No.: 6425-24-7
• Molecular Formula: C7H5Br2F
• Molecular Weight: 267.923
• European Community (EC) Number: 613-528-7
• DSSTox Substance ID: DTXSID201300198
• Nikkaji Number: J1.868.142K
• Mol file: 6425-24-7.mol

Synonyms:1-(Dibromomethyl)-4-fluorobenzene;6425-24-7;4-fluorobenzalbromide;4-(Dibromomethyl)fluorobenzene;SCHEMBL2732165;ZQNQSIPAAGRZAU-UHFFFAOYSA-N;DTXSID201300198;MFCD25965720;4-(Dibromomethyl)fluorobenzene, 94%

Chemical Property of 1-(Dibromomethyl)-4-fluorobenzene

Chemical Property:

• Vapor Pressure: 0.0867mmHg at 25°C
• Boiling Point: 233.1oC at 760 mmHg
• Flash Point: 94.8oC
• PSA: 0.00000
• Density: 1.954g/cm3
• LogP: 3.61410
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 267.87215
• Heavy Atom Count: 10
• Complexity: 97.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(Br)Br)F

Technology Process of 1-(Dibromomethyl)-4-fluorobenzene

There total 6 articles about 1-(Dibromomethyl)-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

p-fluorotoluene (352-32-9) → 1-(dibromomethyl)-4-fluorobenzene (6425-24-7)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In Diethyl carbonate; for 1h; Reflux; Microwave irradiation;

DOI:10.1039/c0gc00794c

Reference yield:

p-fluorotoluene (352-32-9) → 1-(dibromomethyl)-4-fluorobenzene (6425-24-7) + 4-Fluorobenzyl bromide (459-46-1)

Guidance literature:

With bromine; In tetrachloromethane; at 20 ℃; for 0.00305556h; Overall yield = 73 %Spectr.; Flow reactor; UV-irradiation;

DOI:10.1002/chem.201402303

Reference yield:

4-Fluorobenzyl bromide (459-46-1) → 1-(dibromomethyl)-4-fluorobenzene (6425-24-7)

Guidance literature:

With N-Bromosuccinimide; In benzene; at 80 ℃; Rate constant; Irradiation;

upstream raw materials:

p-fluorotoluene

4-Fluorobenzyl bromide

4-fluorobenzal chloride

4-fluorobenzaldehyde

Downstream raw materials:

p-FC₆H₄CH(SCF₃)2

4-fluorobenzaldehyde

5-(4-fluorophenyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole

5-(4-fluorophenyl)-3-phenyl-1,2,4-oxadiazole