2-Chloroethanesulfonyl fluoride

Base Information

• Chemical Name: 2-Chloroethanesulfonyl fluoride
• CAS No.: 762-70-9
• Molecular Formula: C2H4ClFO2S
• Molecular Weight: 146.57
• Hs Code.: 2904909090
• DSSTox Substance ID: DTXSID1073236
• Nikkaji Number: J1.551.519H
• Wikidata: Q82001609
• Mol file: 762-70-9.mol

Synonyms:2-Chloroethanesulfonyl fluoride;762-70-9;Ethanesulfonyl fluoride, 2-chloro-;2-CHLOROETHANE-1-SULFONYL FLUORIDE;FSO2CH2CH2Cl;2-Chloroethane sulfonylfluoride;SCHEMBL1844002;DTXSID1073236;MFCD01937909;AKOS006384439;AT26976;LS-65690;CS-0212429;EN300-216212

Chemical Property of 2-Chloroethanesulfonyl fluoride

Chemical Property:

• Vapor Pressure: 9.57mmHg at 25°C
• Boiling Point: 135.4°Cat760mmHg
• Flash Point: 35.7°C
• PSA: 42.52000
• Density: 1.474g/cm³
• LogP: 1.60530
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 145.9604564
• Heavy Atom Count: 7
• Complexity: 123

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloroethanesulfonylfluoride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): A poison by ingestion and skin contact. Low toxicity by inhalation. A severe eye irritant.
• Hazard Codes: A poison by ingestion and skin contact. Low toxicity by inhalation. A severe eye irritant.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCl)S(=O)(=O)F

Technology Process of 2-Chloroethanesulfonyl fluoride

There total 3 articles about 2-Chloroethanesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Chloroethanesulfonyl chloride (1622-32-8) → 2-chloroethanesulfonyl fluoride (762-70-9)

Guidance literature:

With potassium hydrogenfluoride; In water; at 20 ℃; for 2h;

DOI:10.1039/d0nj05603k

Reference yield:

→ 2-chloroethanesulfonyl fluoride (762-70-9) + 2-Chloroethanesulfonyl chloride (1622-32-8)

Guidance literature:

Reference yield:

Ethanesulfonyl chloride (594-44-5) → 2-chloroethanesulfonyl fluoride (762-70-9)

Guidance literature:

With chlorine; im UV-Licht;

upstream raw materials:

2-Chloroethanesulfonyl chloride

Ethanesulfonyl chloride

Downstream raw materials:

ethylenesulfonyl fluoride

2-(Methylphenylamino)ethansulfonylfluorid

Refernces

• 1、 Zhang, Xu,Moku, Balakrishna,Leng, Jing,Rakesh,Qin, Hua-Li. "2-Azidoethane-1-sulfonylfluoride (ASF): A Versatile Bis-clickable Reagent for SuFEx and CuAAC Click Reactions". . p. 1763 - 1769. Retrieved 2019.
• 2、 -. "Sulfur(VI) fluoride compounds and methods for the preparation thereof". Page/Page column 19; 36; 37; 51. . Retrieved 2018/11/23.