Acetic acid, oxo-, (4-methoxyphenyl)methyl ester

Base Information

• Chemical Name: Acetic acid, oxo-, (4-methoxyphenyl)methyl ester
• CAS No.: 64370-70-3
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.187
• DSSTox Substance ID: DTXSID00446404
• Nikkaji Number: J2.634.343G
• Wikidata: Q82265033
• Mol file: 64370-70-3.mol

Synonyms:p-Methoxybenzyl glyoxylate;64370-70-3;Acetic acid, oxo-, (4-methoxyphenyl)methyl ester;4-methoxybenzyl glyoxylate;SCHEMBL8016679;DTXSID00446404;ATXQTOYMZRUNJQ-UHFFFAOYSA-N;(4-Methoxyphenyl)glyoxylic acid methyl ester

Chemical Property of Acetic acid, oxo-, (4-methoxyphenyl)methyl ester

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 194.05790880
• Heavy Atom Count: 14
• Complexity: 194

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)COC(=O)C=O

Technology Process of Acetic acid, oxo-, (4-methoxyphenyl)methyl ester

There total 2 articles about Acetic acid, oxo-, (4-methoxyphenyl)methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-p-methoxybenzyl fumarate (114409-25-5) + dimethylsulfide (75-18-3) → 4-methoxybenzyl glyoxylate (64370-70-3) + p-Methoxybenzyl glyoxylate monohydrate

Guidance literature:

In dichloromethane; ethyl acetate;

Reference yield:

→ 4-methoxybenzyl glyoxylate (64370-70-3)

Guidance literature:

entspr. L-(+)-Weinsaeure-diester + Bleitetraacetat.;

Reference yield: 63.0%

4-methoxybenzyl glyoxylate (64370-70-3) + Acetic acid 1-(5-oxo-pyrrolidin-2-yl)-allyl ester (132114-40-0) → [2-(1-Acetoxy-allyl)-5-oxo-pyrrolidin-1-yl]-(triphenyl-λ5-phosphanylidene)-acetic acid 4-methoxy-benzyl ester (132114-42-2)

Guidance literature:

DOI:10.1016/S0040-4039(00)97208-3

upstream raw materials:

di-p-methoxybenzyl fumarate

dimethylsulfide

Downstream raw materials:

[2-(1-Acetoxy-allyl)-5-oxo-pyrrolidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-methoxy-benzyl ester

((2R,3R)-2-Allyl-3-bromo-4-oxo-azetidin-1-yl)-hydroxy-acetic acid 4-methoxy-benzyl ester

{(2R,3S)-2-((R)-3-Acetoxy-1-methyl-2-oxo-propyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-methoxy-benzyl ester

[(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-((R)-(S)-1-oxiranyl-ethyl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-methoxy-benzyl ester