3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol

Base Information

Chemical Name:3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol
CAS No.:64432-04-8
Molecular Formula:C23H34O2
Molecular Weight:342.51500
Hs Code.:
DSSTox Substance ID:DTXSID201138797
Nikkaji Number:J146.863D

Synonyms:64432-04-8;Grifolin monomethyl ether;3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol;3-methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]phenol;3-Methoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)phenol;Phenol, 3-methoxy-5-methyl-2-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-, (E,E)-;starbld0005553;DTXSID201138797;AKOS040761804;3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]phenol;3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol #

Suppliers and Price of 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol

Chemical Property:

PSA：29.46000
LogP:6.67090
XLogP3:7.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:342.255880323
Heavy Atom Count:25
Complexity:469

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)OC)CC=C(C)CCC=C(C)CCC=C(C)C)O
Isomeric SMILES:CC1=CC(=C(C(=C1)OC)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O

Technology Process of 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol

There total 4 articles about 3-Methoxy-5-methyl-2-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 83897-47-6
3-Methylcyclobutenon

: 89711-19-3
(4E,8E)-1-Methoxy-5,9,13-trimethyl-tetradeca-4,8,12-trien-1-yne

: 64432-04-8
3-methoxy-5-methyl-2-<(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl>phenol

Guidance literature:: In benzene; at 80 ℃; for 4h;
DOI:10.1021/jo00183a043

Reference yield:

: 64432-03-7
1,3-dimethoxy-5-methyl-2-<(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl>benzene

: 64432-04-8
3-methoxy-5-methyl-2-<(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl>phenol

Guidance literature:: With sodium thioethylate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 110 ℃; for 1.33333h;
DOI:10.1246/bcsj.67.1178

Reference yield:

: 24163-93-7,24163-94-8,56881-57-3,6874-67-5,28290-41-7
farnesyl bromide

: 64432-04-8
3-methoxy-5-methyl-2-<(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl>phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / BuLi / diethyl ether; hexane; hexamethylphosphoric acid triamide

2: EtSNa / hexamethylphosphoric acid triamide / 1.33 h / 110 °C

With n-butyllithium; sodium thioethylate; In N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; hexane;
DOI:10.1246/bcsj.67.1178