[2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol

Base Information

Chemical Name:[2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol
CAS No.:64465-86-7
Molecular Formula:C19H23NOS
Molecular Weight:313.45700
Hs Code.:
DSSTox Substance ID:DTXSID10507353
Wikidata:Q82363532

Synonyms:64465-86-7;SCHEMBL11630768;DTXSID10507353;[2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol

Suppliers and Price of [2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of [2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol

Chemical Property:

PSA：48.77000
LogP:4.25390
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:313.15003553
Heavy Atom Count:22
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CC2=CC=CC=C2SC3=CC=CC=C3CO

Technology Process of [2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol

There total 8 articles about [2-({2-[(Piperidin-1-yl)methyl]phenyl}sulfanyl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62220-53-5
2-carbethoxy-2'-chlorocarbonyldiphenyl sulfide

: 64465-86-7
2-(hydroxymethyl)-2'-(piperidinomethyl)diphenyl sulfide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / 3 h / Ambient temperature

2: LiAlH₄

With lithium aluminium tetrahydride; triethylamine; In acetonitrile;
DOI:10.1021/jo00321a020

Reference yield:

: 22219-02-9
2,2'-thiodibenzoic acid

: 64465-86-7
2-(hydroxymethyl)-2'-(piperidinomethyl)diphenyl sulfide

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / 5 h / 60 °C

2: 0.5 h / Heating

3: 37 percent / KOH / ethanol / 96 h / Ambient temperature

4: 20.1 g / thionyl chloride

5: triethylamine / acetonitrile / 3 h / Ambient temperature

6: LiAlH₄

With potassium hydroxide; lithium aluminium tetrahydride; thionyl chloride; triethylamine; In ethanol; acetonitrile;
DOI:10.1021/jo00321a020

Reference yield:

: 62220-52-4
2-carbethoxy-2'-carboxydiphenyl sulfide

: 64465-86-7
2-(hydroxymethyl)-2'-(piperidinomethyl)diphenyl sulfide

Guidance literature:: Multi-step reaction with 3 steps

1: 20.1 g / thionyl chloride

2: triethylamine / acetonitrile / 3 h / Ambient temperature

3: LiAlH₄

With lithium aluminium tetrahydride; thionyl chloride; triethylamine; In acetonitrile;
DOI:10.1021/jo00321a020