2-(1H-benzimidazol-2-yl)acetohydrazide

Base Information

Chemical Name:2-(1H-benzimidazol-2-yl)acetohydrazide
CAS No.:19731-02-3
Molecular Formula:C9H10 N4 O
Molecular Weight:190.205
Hs Code.:2933990090
European Community (EC) Number:875-167-3
DSSTox Substance ID:DTXSID10350482
Wikidata:Q82126451
Mol file:19731-02-3.mol

Synonyms:19731-02-3;2-(1H-benzimidazol-2-yl)acetohydrazide;2-(1H-1,3-benzodiazol-2-yl)acetohydrazide;2-(1H-Benzo[d]imidazol-2-yl)acetohydrazide;(1H-Benzoimidazol-2-Yl)-Acetic Acid Hydrazide;(1h-benzoimidazol-2-yl)acetic acid hydrazide;TimTec1_005461;Oprea1_042089;Oprea1_159648;SCHEMBL5307911;DTXSID10350482;HMS1549I05;1H-Benzo[d]imidazol-2-acetohydrazide;1H-benzo[d]imidazole-2-acethydrazide;AKOS000122613;CS-0219347;EN300-03781;(1H-BENZOIMIDAZOL-2-YL)-ACETICACIDHYDRAZIDE;J-504651;Z56881229

Suppliers and Price of 2-(1H-benzimidazol-2-yl)acetohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1H-1,3-benzodiazol-2-yl)acetohydrazide
50mg
$ 65.00

TRC
2-(1H-1,3-benzodiazol-2-yl)acetohydrazide
10mg
$ 45.00

American Custom Chemicals Corporation
(1H-BENZOIMIDAZOL-2-YL)-ACETIC ACID HYDRAZIDE 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
(1H-BENZOIMIDAZOL-2-YL)-ACETIC ACID HYDRAZIDE 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
(1H-BENZOIMIDAZOL-2-YL)-ACETIC ACID HYDRAZIDE 95.00%
1G
$ 692.46

AK Scientific
2-(1H-Benzimidazol-2-yl)acetohydrazide
2.5g
$ 664.00

AK Scientific
2-(1H-Benzimidazol-2-yl)acetohydrazide
500mg
$ 289.00

AK Scientific
2-(1H-Benzimidazol-2-yl)acetohydrazide
100mg
$ 172.00

Total 6 raw suppliers

Chemical Property of 2-(1H-benzimidazol-2-yl)acetohydrazide

Chemical Property:

Vapor Pressure:3.51E-13mmHg at 25°C
Melting Point:204-205 °C
Boiling Point:574°Cat760mmHg
PKA:11.53±0.10(Predicted)
Flash Point:300.9°C
PSA：83.80000
Density:1.383g/cm³
LogP:1.18650
XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:190.08546096
Heavy Atom Count:14
Complexity:221

Purity/Quality:

99% ^*data from raw suppliers

2-(1H-1,3-benzodiazol-2-yl)acetohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=N2)CC(=O)NN
Uses 2-(1H-1,3-Benzodiazol-2-yl)acetohydrazide is used in the preparation of new benzimidazoles derivatives with anthelmintic properties.

Technology Process of 2-(1H-benzimidazol-2-yl)acetohydrazide

There total 5 articles about 2-(1H-benzimidazol-2-yl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 14741-71-0
ethyl (1H-benzimidazol-2-yl)acetate

: 19731-02-3
2-(1H-benzo[d]imidazol-2-yl)acetohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 0.5h; Heating;

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 19731-02-3
2-(1H-benzo[d]imidazol-2-yl)acetohydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: 10 h / Reflux; Dean-Stark

2: hydrogenchloride; benzenesulfonic acid / water / 4 h / Reflux

3: sulfuric acid / 7 h / Reflux

4: hydrazine hydrate / ethanol / Reflux

With hydrogenchloride; sulfuric acid; hydrazine hydrate; benzenesulfonic acid; In ethanol; water;
DOI:10.1016/j.ejmech.2016.12.014

Reference yield:

: 4414-88-4
1H-benzimidazol-2-acetonitrile

: 19731-02-3
2-(1H-benzo[d]imidazol-2-yl)acetohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; benzenesulfonic acid / water / 4 h / Reflux

2: sulfuric acid / 7 h / Reflux

3: hydrazine hydrate / ethanol / Reflux

With hydrogenchloride; sulfuric acid; hydrazine hydrate; benzenesulfonic acid; In ethanol; water;
DOI:10.1016/j.ejmech.2016.12.014