Technology Process of 2H-Pyran-2-ol,3-(1,1-dimethylethyl)tetrahydro-,acetate(9CI)
There total 6 articles about 2H-Pyran-2-ol,3-(1,1-dimethylethyl)tetrahydro-,acetate(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; dmap;
In
dichloromethane; toluene;
at -78 - 23 ℃;
for 24.5h;
DOI:10.1021/ja037935a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: DIBAL-H / toluene; CH2Cl2 / 5 h / -78 °C
2: 0.341 g / pyridine; 4-dimethylaminopyridine / toluene; CH2Cl2 / 24.5 h / -78 - 23 °C
With
pyridine; dmap; diisobutylaluminium hydride;
In
dichloromethane; toluene;
DOI:10.1021/ja037935a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 74 percent / H2SO4 / 24 h / 84 °C
2.1: diisopropylamine; n-BuLi / tetrahydrofuran; hexane / 4 h / -78 °C
2.2: 89 percent / tetrahydrofuran; hexane / 16 h / 23 °C
3.1: BH3*SMe2 / tetrahydrofuran / 72 h / 23 °C
3.2: 51 percent / NaOH; aq. H2O2 / tetrahydrofuran / 48 h / 23 °C
4.1: 81 percent / camphorsulfonic acid / benzene / 24 h / 80 °C
5.1: DIBAL-H / toluene; CH2Cl2 / 5 h / -78 °C
6.1: 0.341 g / pyridine; 4-dimethylaminopyridine / toluene; CH2Cl2 / 24.5 h / -78 - 23 °C
With
pyridine; dmap; n-butyllithium; dimethylsulfide borane complex; sulfuric acid; camphor-10-sulfonic acid; diisobutylaluminium hydride; diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane; toluene; benzene;
DOI:10.1021/ja037935a
