4-alanylaminoantipyrine

Base Information

• Chemical Name: 4-alanylaminoantipyrine
• CAS No.: 62989-75-7
• Molecular Formula: C₁₄H₁₈N₄O₂
• Molecular Weight: 274.323
• Hs Code.: 2933199090
• Mol file: 62989-75-7.mol

Synonyms:4-Alanylaminoantipyrine;DL-Alanine-4-antipyrineamide;WK 32;4-D,L-Alanylamino-antipyrin;Propanamide,2-amino-N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-,(+-);

Chemical Property of 4-alanylaminoantipyrine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 85.54000
• Density: 1.27g/cm³
• LogP: 2.11990

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-alanylaminoantipyrine

There total 2 articles about 4-alanylaminoantipyrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylcarbamoyl)-ethyl]-benzamide (81216-97-9,151921-17-4) → 4-D,L-Alanylamino-antipyrin (62989-75-7,62951-85-3)

Guidance literature:

With sodium hydroxide; In benzene; for 6h; Heating;

Reference yield:

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one (83-07-8) → 4-D,L-Alanylamino-antipyrin (62989-75-7,62951-85-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 8 h / Ambient temperature

2: NaOH / benzene / 6 h / Heating

With sodium hydroxide; dicyclohexyl-carbodiimide; In dichloromethane; benzene;

upstream raw materials:

N-[1-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylcarbamoyl)-ethyl]-benzamide

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one