3-Pyridinesulfonic acid, 6-phenyl-2-[(1-phenylethyl)amino]-, phenyl ester

Base Information

• Chemical Name: 3-Pyridinesulfonic acid, 6-phenyl-2-[(1-phenylethyl)amino]-, phenyl ester
• CAS No.: 646053-50-1
• Molecular Formula: C₂₅H₂₂N₂O₃S
• Molecular Weight: 430.527
• Mol file: 646053-50-1.mol

Synonyms:

Chemical Property of 3-Pyridinesulfonic acid, 6-phenyl-2-[(1-phenylethyl)amino]-, phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinesulfonic acid, 6-phenyl-2-[(1-phenylethyl)amino]-, phenyl ester

There total 3 articles about 3-Pyridinesulfonic acid, 6-phenyl-2-[(1-phenylethyl)amino]-, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

Phenylpropargyl aldehyde (2579-22-8) + (+/-)-(E)-phenyl 2-amino-2-[1-(phenylethyl)amino]ethensulfonate (646053-49-8) → (+/-)-phenyl 6-phenyl-2-[(1-phenylethyl)amino]pyridine-3-sulfonate (646053-50-1)

Guidance literature:

With acetic acid; In ethanol; for 5h; Heating;

DOI:10.1055/s-2003-40524

Reference yield:

rac-methylbenzylamine (618-36-0) → (+/-)-phenyl 6-phenyl-2-[(1-phenylethyl)amino]pyridine-3-sulfonate (646053-50-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / ethanol / 72 h / 20 °C

2: 35 percent / HOAc / ethanol / 5 h / Heating

With acetic acid; In ethanol;

DOI:10.1055/s-2003-40524

Reference yield:

ethyl 2-(phenoxysulfonyl)ethanimidoate → (+/-)-phenyl 6-phenyl-2-[(1-phenylethyl)amino]pyridine-3-sulfonate (646053-50-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / ethanol / 72 h / 20 °C

2: 35 percent / HOAc / ethanol / 5 h / Heating

With acetic acid; In ethanol;

DOI:10.1055/s-2003-40524

upstream raw materials:

Phenylpropargyl aldehyde

(+/-)-(E)-phenyl 2-amino-2-[1-(phenylethyl)amino]ethensulfonate

rac-methylbenzylamine

Refernces