1,1'-Biphenyl, 2-methoxy-2'-nitro-

Base Information

• Chemical Name: 1,1'-Biphenyl, 2-methoxy-2'-nitro-
• CAS No.: 6460-92-0
• Molecular Formula: C13H11NO3
• Molecular Weight: 229.235
• DSSTox Substance ID: DTXSID10355972
• Nikkaji Number: J2.259.163K
• Wikidata: Q82135077
• Mol file: 6460-92-0.mol

Synonyms:6460-92-0;1-(2-methoxyphenyl)-2-nitrobenzene;1,1//'-Biphenyl, 2-methoxy-2//'-nitro-;1,1'-Biphenyl, 2-methoxy-2'-nitro-;2-nitro-2'-methoxy-1,1'-biphenyl;SCHEMBL6425266;DTXSID10355972;AG-777/25006393

Chemical Property of 1,1'-Biphenyl, 2-methoxy-2'-nitro-

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 229.07389321
• Heavy Atom Count: 17
• Complexity: 264

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1C2=CC=CC=C2[N+](=O)[O-]

Technology Process of 1,1'-Biphenyl, 2-methoxy-2'-nitro-

There total 8 articles about 1,1'-Biphenyl, 2-methoxy-2'-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

o-nitroiodobenzene (609-73-4) + 2-Methoxyphenylboronic acid (5720-06-9) → 2-methoxy-2'-nitrobiphenyl (6460-92-0)

Guidance literature:

With potassium carbonate; palladium diacetate; In methanol; water; at 20 ℃; for 28h;

DOI:10.1021/jo051589t

Reference yield: 94.0%

2-Methoxyphenylboronic acid (5720-06-9) + 2-Chloronitrobenzene (88-73-3) → 2-methoxy-2'-nitrobiphenyl (6460-92-0)

Guidance literature:

With potassium phosphate tribasic trihydrate; (2-(anthracen-9-yl)-1H-inden-3-yl)dicyclohexylphosphine; palladium diacetate; In water; isopropyl alcohol; toluene; at 90 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c7ob00178a

Reference yield: 89.0%

2-nitrobenzenediazonium 4-methylbenzenesulfonate (1059625-66-9) + 2-Methoxyphenylboronic acid (5720-06-9) → 2-methoxy-2'-nitrobiphenyl (6460-92-0)

Guidance literature:

With palladium diacetate; In water; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1055/s-0036-1588919

upstream raw materials:

2-bromoanisole

o-nitroiodobenzene

4-iodoanisol

2-nitrophenylboronic acid

Downstream raw materials:

2-(2'-methoxyphenyl)aniline

4-methoxy-9H-carbazole

2′-amino-[1,1′-biphenyl]-2-ol