Technology Process of 2,4-Thiazolidinedione,
5-[[4-[2-bromo-2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-
There total 16 articles about 2,4-Thiazolidinedione,
5-[[4-[2-bromo-2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
piperidine; acetic acid;
In
toluene;
Heating;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen / tetrahydrofuran / 12 h
2.1: zinc; acetic acid / 15 h / 25 - 30 °C
3.1: N-Bromosuccinimide / tert-butyl alcohol; water / 1.5 h / 25 °C / Large scale
3.2: 0.75 h / Large scale
3.3: PEG 4000 / 17 h / 78 °C / Large scale
4.1: phosphorus tribromide / chloroform / 1 h / Reflux
5.1: acetic acid; piperidine / toluene / Heating
With
piperidine; N-Bromosuccinimide; hydrogen; phosphorus tribromide; acetic acid; zinc;
In
tetrahydrofuran; chloroform; water; toluene; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / tert-butyl alcohol / 1.17 h / Reflux
1.2: 11 h / Reflux
2.1: phosphorus tribromide / chloroform / 1 h / Reflux
3.1: acetic acid; piperidine / toluene / Heating
With
piperidine; phosphorus tribromide; potassium carbonate; acetic acid;
In
chloroform; toluene; tert-butyl alcohol;
